Ingredient Dictionary

BENZOYL CHLORIDE

Benzoyl chloride is an acyl chloride consisting of benzene in which a hydrogen is replaced by an acyl chloride group.

Definition

Benzoyl chloride is an acyl chloride consisting of benzene in which a hydrogen is replaced by an acyl chloride group. It is an important chemical intermediate for the manufacture of other chemicals, dyes, perfumes, herbicides and pharmaceuticals. It has a role as a carcinogenic agent. It is a member of benzenes and an acyl chloride. It is functionally related to a benzoic acid.

Source: PubChem

US FDA substance register · UNII VTY8706W36 · registered name Benzoyl Chloride · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONING

Safety & regulatory references

Korea’s toxic-substance GHS classification: Danger · H314 (category 1) · H331 (category 3) · H302 (category 4) · +1 more

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

BENZOYL CHLORIDEINCI벤조일클로라이드Korean label name (MFDS standard)

CAS No.chemical registry number: 98-88-4
EC No.EU chemical inventory number: 202-710-8
DTXSIDUS EPA chemical ID: DTXSID9026631
DTXCIDUS EPA compound ID: DTXCID106631

IUPAC: Benzoyl chloride
Molecular formula: C7H5ClO
Molecular weight: 140.57 g/mol

Measured properties

Appearance: liquid
Colour: colourless
pH: 2 (1 g/ℓ, 20℃)
Melting/freezing point: -1 ℃
Initial boiling point and range: 197.2 ℃(760 ㎜Hg)
Flash point: 72 ℃
Flammability (solid, gas): not flammable
Upper/lower flammability or explosive limits: 27 / 2.5 %
Vapour pressure: 0.084 ㎪ (25℃)
Water solubility: 10500 ㎎/ℓ (25℃)
Vapour density: 1.22 g/㎤ (20℃)
Relative density: 1.21
n-Octanol/water partition coefficient (Kow): 1.44 (log Pow, 21℃)
Auto-ignition temperature: 600 ℃ (1 atm)
Molecular weight: 140.567

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Processing aids not otherwise specified1
Polymerization promoter1
Insulators1
Softener and conditioner1
Intermediate1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

10 skin studies and 2 eye studies are on record.

Classed as highly irritating1Classed as moderate1

The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 12 studies

Category 1A-1C
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Skin Corr. 1B
Skin Irritation · Authoritative
Skin Sens. 1
Skin Sensitization · Authoritative
Skin corrosion - category 1B
Skin Irritation · Screening
Skin sensitisation - category 1
Skin Sensitization · Screening
Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Category 6.5B (Category 1)
Skin Sensitization · Read Across
Category 8.2B (Category 1B)
Skin Irritation · Read Across
Category 1
Eye Irritation · Screening
Category 8.3A (Category 1)
Eye Irritation · Read Across