Benzoyl chloride is an acyl chloride consisting of benzene in which a hydrogen is replaced by an acyl chloride group.
定义
Benzoyl chloride is an acyl chloride consisting of benzene in which a hydrogen is replaced by an acyl chloride group. It is an important chemical intermediate for the manufacture of other chemicals, dyes, perfumes, herbicides and pharmaceuticals. It has a role as a carcinogenic agent. It is a member of benzenes and an acyl chloride. It is functionally related to a benzoic acid.
来源: PubChem
美国FDA 物质登记 · UNII VTY8706W36 · 登记名称 Benzoyl Chloride · 单一化学物质
化妆品中的作用
安全与法规参考
韩国有毒物质 GHS 分类: 危险 · H314 (第1类) · H331 (第3类) · H302 (第4类) · 另有 1 项
Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 98-88-4
- EC No.欧盟化学品目录编号
- 202-710-8
- DTXSID美国EPA化学品编号
- DTXSID9026631
- DTXCID美国EPA化合物编号
- DTXCID106631
- IUPAC
- Benzoyl chloride
- 分子式
- C7H5ClO
- 分子量
- 140.57 g/mol
实测物性
- 性状
- 液体
- 颜色
- 无色
- pH
- 2 (1 g/ℓ, 20℃)
- 熔点/凝固点
- -1 ℃
- 初沸点和沸程
- 197.2 ℃(760 ㎜Hg)
- 闪点
- 72 ℃
- 易燃性（固体、气体）
- 不易燃
- 燃烧或爆炸范围上限/下限
- 27 / 2.5 %
- 蒸气压
- 0.084 ㎪ (25℃)
- 溶解度
- 10500 ㎎/ℓ (25℃)
- 蒸气密度
- 1.22 g/㎤ (20℃)
- 比重
- 1.21
- 正辛醇/水分配系数（Kow）
- 1.44 (log Pow, 21℃)
- 自燃温度
- 600 ℃ (1 atm)
- 分子量
- 140.567
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 5 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Processing aids not otherwise specified1
- Polymerization promoter1
- Insulators1
- Softener and conditioner1
- Intermediate1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 10 项、眼部试验 2 项。
各项试验结论不一（最多的结论占 50%），因此不能断定该成分有刺激性。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 12 项试验
- Category 1A-1C
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Skin Corr. 1B
Skin Irritation · Authoritative - Skin Sens. 1
Skin Sensitization · Authoritative - Skin corrosion - category 1B
Skin Irritation · Screening - Skin sensitisation - category 1
Skin Sensitization · Screening - Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Category 8.2B (Category 1B)
Skin Irritation · Read Across - Category 1
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across
来源: 美国EPA CompTox
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- [Carcinogenicity in mice by inhalation of benzotrichloride and benzoyl chloride]. · 1986