Gloshell
Ingredients

Ingredient Dictionary

BENZOYL PEROXIDE

Benzoyl peroxide is a carbonyl compound.

Molecular structure

Definition

Benzoyl peroxide is a carbonyl compound.

Source: PubChem

US FDA substance register · UNII W9WZN9A0GM · registered name Benzoyl peroxide · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Oxidises other ingredientsOXIDISING

Points to consider

FDA-approved for acne treatment at concentrations between 2.5% and 10%. Considered safe for topical use. Possible side effects include dryness, redness, peeling, or mild irritation, especially when used in higher concentrations or combined with other potent actives.

Usage reference

Benzoyl Peroxide works by releasing oxygen free radicals, which kill Cutibacterium acnes (formerly Propionibacterium acnes), the bacteria responsible for acne. It also helps to exfoliate dead skin cells and reduce comedones by promoting skin cell turnover, which prevents clogged pores.

Safety & regulatory references

Restricted or banned
Argentina · Brazil · China · South Korea
Restricted
United Kingdom

Source: MFDS (Korea) cosmetic regulatory information · ASEAN Cosmetic Directive · EU Cosmetics Regulation · Health Canada Cosmetic Ingredient Hotlist · UK cosmetics regulations (OPSS)

ASEAN

  • Field of application and/or use : Artificial nail systems
  • Maximum authorised concentration in the finished cosmetic product : 0.7 % (After mixing for use)
  • Other limitations and requirements : Professional use only
  • Conditions of use and warning which must be printed on the labels : • For professional use only • Avoid skin contact • Read directions for use carefully

Canada

  • Conditions of Use by product type : (a) Not permitted in products to be applied to the skin. (b) Products to be applied to the fingernails or in hair dyes
  • Maximum Concentration Permitted : b) 10% as a catalyst

European Union

  • Product Type, body parts : Artificial nail systems
  • Maximum concentration in ready for use preparation : 0.7% (after mixing for use)
  • Other : Professional use
  • Wording of conditions of use and warnings : For professional use only Avoid skin contact Read directions for use carefully

Source: MFDS (Korea) cosmetic regulatory information

Korea’s toxic-substance GHS classification: Danger · H241 (category 2) · H319 (category 2) · H400 (category 1) · +1 more

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex III (restricted substances), entry 94 · maximum concentration 0.7% (after mixing for use) · applies to Artificial nail systems

Source: EU restricted substances (Annex III)

Restriction III/94

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name 過酸化ベンゾイル: 本品は、次の化学式で表される過酸化物である。

Source: JCIA labelling names (Japan)

Names & identifiers

BENZOYL PEROXIDEINCI벤조일퍼옥사이드Korean label name (MFDS standard)Peroxide, dibenzoylSynonym過酸化ベンゾイルJapanese labelling name
CAS No.chemical registry number
94-36-0
EC No.EU chemical inventory number
202-327-6
DTXSIDUS EPA chemical ID
DTXSID6024591
DTXCIDUS EPA compound ID
DTXCID001072
Molecular formula
C14H10O4
Molecular weight
242.23 g/mol

Measured properties

Appearance
Benzoyl peroxide appears as odorless white powder or granules. Sinks in water. (USCG, 1999) · Liquid, CBI, Dry Powder, Wet Solid
Odour
Faint, benzaldehyde-like odor.
Boiling point
Decomposes explosively (NTP, 1992) · Decomposes explosively above melting point. Does not reach boiling point.
Melting point
217 to 221 °F (decomposes) (NTP, 1992) · 103 - 106
Solubility
less than 1 mg/mL at 79 °F (NTP, 1992) · <1%
Density
1.334 at 59 °F (USCG, 1999) - Denser than water, will sink · 1.3340 at 25 °C
Melting/freezing point
103~106 ℃
Flash point
176 ℉
Vapour pressure
0.1 (torr, at 20℃)
Water solubility
9.1 ㎎/ℓ (at 25℃)
Vapour density
8.4
Relative density
1.334 (at 25℃)
n-Octanol/water partition coefficient (Kow)
3.46
Auto-ignition temperature
80 ℃
Decomposition temperature
1551.7 (kcal/mole)
Molecular weight
242.24

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 81 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Catalyst40
  • Chemical reaction regulator13
  • Hardener10
  • Oxidizing agent3
  • Processing aids not otherwise specified3
  • Adhesion/cohesion promoter2
  • Pharmaceutical (EPA)1
  • Dye1
8 other uses
  • Food preservative (EPA)1
  • Sealant (barrier)1
  • Intermediate1
  • Stabilizing agent1
  • Filler1
  • Plasticizer1
  • Elasticizer1
  • Polymerization promoter1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

8 skin studies and 6 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 14 studies
  • Not classified
    Skin Irritation · Screening
  • Category 6.5B (Category 1)
    Skin Sensitization · Read Across
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · equivalent or similar to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • Category 1
    Skin Sensitization · Screening
  • Skin Sens. 1
    Skin Sensitization · Screening
  • Skin Sens. 1
    Skin Sensitization · Authoritative
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • Moderate or Mild Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
  • Eye Irrit. 2
    Eye Irritation · Screening
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across
  • Category 2
    Eye Irritation · Screening
  • Eye Irrit. 2
    Eye Irritation · Authoritative
  • Moderate or Mild Irritation
    eye irritation: in vivo · Screening · other guideline: US FDA, 21 CFR, Part 191, Hazardous substances test for eye irritants according to

Source: US EPA CompTox dashboard

Related literature

Linked databases 24