Definition
US FDA substance register · UNII 413O6RKS6B · registered name 2-BENZYL-2-(DIMETHYLAMINO)-1-(4-(MORPHOLIN-4-YL)PHENYL)BUTAN-1-ONE · single chemical substance
Benzyl Dimethylamino Morpholinophenyl Butanone is the organic compound that conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Banned
- ASEAN · European Union · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)
Korea’s toxic-substance GHS classification: Danger · H410 (category 1) · H400 (category 1) · H360 (category 1B)
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1614
Restriction II/1614
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 119313-12-1
- EC No.EU chemical inventory number
- 404-360-3
- DTXSIDUS EPA chemical ID
- DTXSID5044786
- DTXCIDUS EPA compound ID
- DTXCID3024786
- IUPAC
- 2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one
- Molecular formula
- C23H30N2O2
- Molecular weight
- 366.505 g/mol
Measured properties
- Appearance
- Large Crystals, Liquid
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 16 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Photosensitizers7
- Processing aids not otherwise specified2
- UV stabilizer2
- Semiconductor and photovoltaic agent2
- Binder1
- Monomers1
- Catalyst1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
6 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Directive 84/449/EEC, B.6 (GPMT) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Directive 84/449/EEC, B.4 according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 1981 according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) 1981 - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to EU Method B.6 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) 84/449/EWG according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) 1981 according to
Source: US EPA CompTox dashboard
Linked databases 16
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- Korea toxic substances GHS register (NIER)
- MFDS (Korea) cosmetic regulatory information
- PubChem
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata