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Ingredient Dictionary

BENZYLPARABEN

Benzyl parahydroxybenzoate is a benzoate ester and a benzyl ester.

Molecular structure

Definition

Benzyl parahydroxybenzoate is a benzoate ester and a benzyl ester.

Source: PubChem

US FDA substance register · UNII 8Y41DYV4VG · registered name BENZYLPARABEN · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Benzylparaben is the ester of benzyl alcohol and p-hydroxybenzoic acid. It conforms to the formula:

Cosmetic roles

Inhibits microbial growthANTIMICROBIAL

Safety & regulatory references

Banned
ASEAN · European Union · United Kingdom
Restricted or banned
Argentina · ASEAN · Brazil · China · European Union · Japan

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 1377

Source: EU prohibited substances (Annex II)

Restriction II/1377 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Amended Safety Assessment of Parabens as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Amended Report on the Safety Assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben and Benzylparaben as used in cosmetic products

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Benzylparaben

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ベンジルパラベン: 本品は、パラヒドロキシ安息香酸とベンジルアルコール（＊）のエステルであり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

BENZYLPARABENINCI벤질파라벤Korean label name (MFDS standard)Benzoic acid, 4-hydroxy-, phenylmethyl esterSynonymベンジルパラベンJapanese labelling name
CAS No.chemical registry number
94-18-8
EC No.EU chemical inventory number
202-311-9
DTXSIDUS EPA chemical ID
DTXSID9022526
DTXCIDUS EPA compound ID
DTXCID202526
IUPAC
Benzyl 4-hydroxybenzoate
Molecular formula
C14H12O3
Molecular weight
228.247 g/mol

Measured properties

Appearance
solid
Colour
white
Molecular weight
228.25 (est.)

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Biocide1
  • Food preservative (EPA)1
  • Preservative1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as highly irritating2Classed as low1

The study conclusions largely agree (67%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · other guideline: as per mentioned below according to
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as per mentioned below
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · other guideline: as per mentioned below according to

Source: US EPA CompTox dashboard

Related literature

Linked databases 22

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