Ingredient Dictionary

BETA-SITOSTEROL

Sitosterol is a member of the class of phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3.

How much products actually contain

9 products state the amountmedian 0.5%

under 0.01% 3
0.01–0.1% 0
0.1–1% 4
1% or more 2

Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.

Of the products containing it, 35 list it before the 1% line and 47 after it (usually 1% or less).

Products using this ingredient

12 of 82 confirmed · likeliest to carry enough first · See all 82

Definition

Sitosterol is a member of the class of phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3. It has a role as an antioxidant, an anticholesteremic drug, a sterol methyltransferase inhibitor, a mouse metabolite and a plant metabolite. It is a stigmastane sterol, a 3beta-hydroxy-Delta(5)-steroid, a C29-steroid, a member of phytosterols and a 3beta-sterol. It derives from a hydride of a stigmastane.

Source: PubChem

US FDA substance register · UNII S347WMO6M4 · registered name β-sitosterol · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps an emulsion from separatingEMULSION STABILISINGProtects colour and scent from lightLIGHT STABILIZERListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCEKeeps skin in good condition (CosIng catch-all)SKIN CONDITIONING

Safety & regulatory references

Reviewed by CIR: Safety Assessment of Phytosterols as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name シトステロール: 本品は、次の化学式で表されるステロールである。

Source: JCIA labelling names (Japan)

Names & identifiers

BETA-SITOSTEROLINCI베타-시토스테롤Korean label name (MFDS standard)Stigmast-5-en-3-ol, (3.beta.)-SynonymシトステロールJapanese labelling name

CAS No.chemical registry number: 83-46-5
EC No.EU chemical inventory number: 201-480-6
DTXSIDUS EPA chemical ID: DTXSID5022481
DTXCIDUS EPA compound ID: DTXCID802481

IUPAC: Stigmast-5-en-3beta-ol
Molecular formula: C29H50O
Molecular weight: 414.718 g/mol

Measured properties

Appearance: Solid
Melting point: 140 °C
Solubility: 10 mg/mL

Values measured on the substance itself, not a specification for a commercial raw material.

Source: PubChem

What products actually use it for

What the 11 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Softener and conditioner3
Emulsifier2
Deodorizer2
Stabilizing agent2
Fragrance1
Pharmaceutical (EPA)1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 0 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 1 studies

SkinIrr2
Skin Irritation · QSAR Predicted