Ingredient Dictionary

BETULINIC ACID

Betulinic acid is a pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents.

Definition

Betulinic acid is a pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties. It has a role as an antineoplastic agent, an antimalarial, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an anti-HIV agent, an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid and a hydroxy monocarboxylic acid. It derives from a hydride of a lupane.

Source: PubChem

US FDA substance register · UNII 4G6A18707N · registered name BETULINIC ACID · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONING

Safety & regulatory references

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ベツリン酸: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

BETULINIC ACIDINCIベツリン酸Japanese labelling name

CAS No.chemical registry number: 472-15-1
EC No.EU chemical inventory number: 207-448-8
DTXSIDUS EPA chemical ID: DTXSID80861974
DTXCIDUS EPA compound ID: DTXCID301506361

IUPAC: 3beta-Hydroxylup-20(29)-en-28-oic acid
Molecular formula: C30H48O3
Molecular weight: 456.711 g/mol

What products actually use it for

What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Softener and conditioner1

Source: US EPA CompTox dashboard