Betulinic acid is a pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents.
定义
Betulinic acid is a pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties. It has a role as an antineoplastic agent, an antimalarial, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an anti-HIV agent, an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid and a hydroxy monocarboxylic acid. It derives from a hydride of a lupane.
来源: PubChem
美国FDA 物质登记 · UNII 4G6A18707N · 登记名称 BETULINIC ACID · 单一化学物质
化妆品中的作用
安全与法规参考
Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 ベツリン酸: 本品は、次の化学式で表される有機化合物である。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
- CAS No.化学物质登记号
- 472-15-1
- EC No.欧盟化学品目录编号
- 207-448-8
- DTXSID美国EPA化学品编号
- DTXSID80861974
- DTXCID美国EPA化合物编号
- DTXCID301506361
- IUPAC
- 3beta-Hydroxylup-20(29)-en-28-oic acid
- 分子式
- C30H48O3
- 分子量
- 456.711 g/mol
产品实际使用的用途
相关文献
- Topical betulinic acid for treatment of equine melanoma and sarcoid · 2026
- Formulation And Evaluation of Betulinic Acid Loaded Transdermal Patches · 2025
- Additive Interactions between Betulinic Acid and Two Taxanes in In Vitro Tests against Four Human Malignant Melanoma Cell Lines · 2022
- Bioactivity of betulinic acid nanoemulsions on skin carcinogenesis in transgenic mice K14E6 · 2022
- Topical Betulinic Acid · 2020