Definition
US FDA substance register · UNII 0AU083F9GJ · registered name BIS-METHOXYETHOXY METHANE · single chemical substance
Cosmetic roles
Surfactant that lifts dirtSURFACTANT - CLEANSINGBase that dissolves other ingredientsSOLVENT
More data — names, identifiers, properties, test records, literature
Names & identifiers
BIS-METHOXYETHOXY METHANEINCI
- CAS No.chemical registry number
- 4431-83-8
- EC No.EU chemical inventory number
- 224-631-8
- DTXSIDUS EPA chemical ID
- DTXSID20196131
- DTXCIDUS EPA compound ID
- DTXCID30118622
- IUPAC
- 2,5,7,10-Tetraoxaundecane
- Molecular formula
- C7H16O4
- Molecular weight
- 164.201 g/mol
Measured properties
- Appearance
- solid
- Melting/freezing point
- &, gt, 300 ℃
- Water solubility
- 300 g/㎖ (25 01 ± 1 01)
- Relative density
- 1.69 (± 0.01 at 20 01 ± 0.5 01)
- n-Octanol/water partition coefficient (Kow)
- &, lt, -3.36 (at 25 01 ± 1 01)
- Auto-ignition temperature
- 350 ℃
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent2
- Surfactant (surface active agent)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
Classed as low3
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to other guideline: OECD guideline 442B (Skin sensitization: Local Lymph node assay: BrdU-ELISA - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin corrosion: in vitro / ex vivo · Screening · EU Method B.46 (In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test) according to - Moderate or Mild Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard