Ingredient Dictionary

BIS-(T-BUTYL BENZOXAZOLYL) THIOPHENE

2,5-bis(5-tert-butyl-2-benzoxazolyl)thiophene is a benzoxazole.

Definition

2,5-bis(5-tert-butyl-2-benzoxazolyl)thiophene is a benzoxazole.

Source: PubChem

US FDA substance register · UNII W7UR9129GP · registered name FLUORESCENT BRIGHTENER 184 · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Bis-(t-Butyl Benzoxazolyl) Thiophene is the organic compound that conforms to the formula

Cosmetic roles

Skin conditioning not covered aboveSKIN CONDITIONING - MISCELLANEOUS

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

BIS-(T-BUTYL BENZOXAZOLYL) THIOPHENEINCI비스(t-부틸벤족사졸릴)티오펜Korean label name (MFDS standard)Benzoxazole, 2,2'-(2,5-thiophenediyl)bis[5-(1,1-dimethylethyl)-Synonym

CAS No.chemical registry number: 7128-64-5
EC No.EU chemical inventory number: 230-426-4
DTXSIDUS EPA chemical ID: DTXSID1048205
DTXCIDUS EPA compound ID: DTXCID3028180

IUPAC: 2,2'-(Thiophene-2,5-diyl)bis(5-tert-butyl-1,3-benzoxazole)
Molecular formula: C26H26N2O2S
Molecular weight: 430.57 g/mol

Measured properties

Appearance: Other Solid, Dry Powder, Large Crystals · Yellow to green solid, [Merck Index] Yellow powder, [Alfa Aesar MSDS]
Flash point: &amp, gt, 350 ℃
Relative density: 1.26g/cm3
Molecular weight: 430.57

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 34 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Brightener28
Pigment2
Dye2
Softener and conditioner1
Processing aids not otherwise specified1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Maurer et al: The Optimization test in the guinea pig, Agents & Actions 5 (2), 174-179, 1975; Predictive evaluation in animals of the contact allergenic potential of medically important substances Contact Dermatitis 4, 321-333, 1978
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to