Bismuth citrate is it is a colour additive.
Definition
Bismuth citrate is it is a colour additive. It contains a citrate(3-).
Source: PubChem
US FDA substance register · UNII N04867Y76N · registered name BISMUTH CITRATE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted or banned
- Japan · South Korea
Source: MFDS (Korea) cosmetic regulatory information
United States
- Eye Area : No
- Generally (Includes Lipsticks) : No
- External Use : Subject to limitations
- Specific Limitations and Comments : Hair on the scalp≤2.0%
Source: MFDS (Korea) cosmetic regulatory information
SCCS opinion: Opinion on Bismuth citrate
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 813-93-4
- EC No.EU chemical inventory number
- 212-390-1
- DTXSIDUS EPA chemical ID
- DTXSID6074330
- DTXCIDUS EPA compound ID
- DTXCID0048214
- IUPAC
- Bismuth(3+) 2-hydroxypropane-1,2,3-tricarboxylate
- Molecular formula
- C6H5BiO7
- Molecular weight
- 398.079 g/mol
Measured properties
- Appearance
- solid
- Colour
- white
- Relative density
- 3.458g/cm3
- Molecular weight
- 398.08
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Dye2
- pH regulating agent1
- Chelating agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) according to other guideline: Note for Guidance on Non-Clinical Tolerance Testing of Medicinal Products, CPMP/SWP/2145/00, adopted March 1, 2001. - Studies Indicate No Significant Irritation
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 438 (Isolated Chicken Eye Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
- THE IMMUNOMODELING ACTIVITY OF BISMUTH CITRATE IN EXPERIMENT 1-CSTL AND LABORATORY OF INDUSTRIAL TOXICOLOGY · 2019
- [Efficacy and safety of 14-day amoxicillin and furazolidone-based quadruple rescue regimen for eradication of Helicobacter pylori: a retrospective study]. · 2014
- Treatment for gastric mucosa-associated lymphoid tissue (MALT) lymphoma. · 2006
- From bench to bedside to bug: an update of clinically relevant advances in the care of persons with Helicobacter pylori- associated diseases. · 2000
- STUDIES IN THE PHARMACOLOGY OF BISMUTH SALTS II. TOXICITY AND URINARY ELIMINATION OF SOLUBLE BISMUTH SALTS · 1926
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- EU SCCS safety opinions
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3 4
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA color additives
- US FDA prohibited and restricted ingredients 2
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata