Definition
US FDA substance register · UNII H19J064BA5 · registered name Bismuth Subnitrate · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted or banned
- South Korea
Source: MFDS (Korea) cosmetic regulatory information
Taiwan
- Maximum concentration : 3%
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 1304-85-4
- EC No.EU chemical inventory number
- 215-136-8
- DTXSIDUS EPA chemical ID
- DTXSID40893872
- DTXCIDUS EPA compound ID
- DTXCID601323910
- IUPAC
- Bismuth(3+) hydroxide nitrate oxide (5/9/4/1)
- Molecular formula
- Bi5H9N4O22
- Molecular weight
- 1461.98 g/mol
Measured properties
- Appearance
- Liquid, Dry Powder · Odorless, slightly hygroscopic solid, [Merck Index] White powder, insoluble, [MSDSonline]
- Odour
- ODORLESS · odourless
- Boiling point
- Decomposes at 260 · BOILING POINT: 260 °C -HNO3 /BIONO3.H2O/
- Melting point
- Decomposes at 260 · 260 °C DECOMP
- Solubility
- Insoluble · PRACTICALLY INSOL IN WATER, ALC, SOL IN DILUTE HYDROCHLORIC ACID & NITRIC ACID
- Density
- 4.928
- pH
- SHOWS ACID TO MOISTENED LITMUS PAPER
- Relative density
- 4.93 ()
- Decomposition temperature
- 260 ℃
- Molecular weight
- 1461.99
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Opacifer1
- Absorbent1
- Catalyst1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Classification not possible
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) according to other guideline: Note for Guidance on Non-Clinical Tolerance Testing of Medicinal Products, CPMP/SWP/2145/00, adopted March 1, 2001. - Studies Indicate No Significant Irritation
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 438 (Isolated Chicken Eye Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to - Classification not possible
Eye Irritation · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
- Pearls & Oy-sters: Bismuth neurotoxicity from use of topical bismuth dressing for burns · 2019
- Surgical management of unilateral gangrenous udder in a cow: A clinical study · 2017
- Re: The need to include BIPP reactions in routine consent: we should not be patching together patch tests for bismuth iodoform paraffin paste allergy · 2008
- Evaluation of endoscopic topical therapy regimens of amoxicillin, bismuth subnitrate, and metronidazole in treating Helicobacter pylori (HP) · 1995
- Untoward Effects of Anti-amebic Drugs · 1934
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- PubChem
- Taiwan FDA cosmetic ingredients
- Taiwan FDA cosmetic regulations
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata