Ingredient Dictionary

BROMOTHYMOL BLUE

Definition

Bromothymol blue is a member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3-bromo-4-hydroxy-5-isopropyl-2-methylphenyl groups. It has a role as a dye, an acid-base indicator and a two-colour indicator. It is a polyphenol, an organobromine compound, a 2,1-benzoxathiole, a sultone and an arenesulfonate ester.

Source: PubChem

US FDA substance register · UNII VGU4LM0H96 · registered name BROMTHYMOL BLUE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Bromothymol Blue is a colour additive that conforms to the formula:

Cosmetic roles

Adds colourCOLORANT

Safety & regulatory references

Restricted: ASEAN · China · Taiwan
Allowed colourant: ASEAN · Taiwan · United Kingdom

Source: MFDS (Korea) cosmetic regulatory information · ASEAN Cosmetic Directive · EU Cosmetics Regulation · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)

Argentina · Brazil

Field of application and/or use : Dye Substances allowed exclusively in products that have short time of skin and hair contact.

European Union

Product Type, body parts : Rinse-off products

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex IV (allowed colourants), entry 151 · maximum concentration Rinse-off products

Source: EU allowed colourants (Annex IV)

Restriction IV/151 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

BROMOTHYMOL BLUEINCI브로모티몰청색Korean label name (MFDS standard)Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis[2-bromo-3-methyl-6-(1-methylethyl)-, S,S-dioxideSynonym

CAS No.chemical registry number: 76-59-5
EC No.EU chemical inventory number: 200-971-2
DTXSIDUS EPA chemical ID: DTXSID3058799
DTXCIDUS EPA compound ID: DTXCID9047831

IUPAC: 3,3-Bis[3-bromo-4-hydroxy-2-methyl-5-(propan-2-yl)phenyl]-2,1lambda~6~-benzoxathiole-1,1(3H)-dione
Molecular formula: C27H28Br2O5S
Molecular weight: 624.38 g/mol

Measured properties

Appearance: Odorless white to cream-colored solid, Available as pure compound, monosodium salt, and dilute solutions, [CHEMINFO] · solid
Melting/freezing point: 201 ℃
Vapour density: 21.55
n-Octanol/water partition coefficient (Kow): 8.99 (est.)
Molecular weight: 624.39

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Dye2

Source: US EPA CompTox dashboard