Definition
US FDA substance register · UNII KY7O12XPOQ · registered name BRUCINE SULFATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Reviewed by CIR: Final Report of the Safety Asessment of Alcohol Denat. including SD Alcohol 3-A, SD Alcohol 30, SD Alcohol 39, SD Alcohol 39-B, SD Alcohol 39-C, SD Alcohol 40, SD Alcohol 40-B, and SD Alcohol 40-C and the denaturants Quassin, Brucin/Brucine Sulfate, and Denatonium Benzoate
CIR reviewed this ingredient and flagged its status as: CIR insufficient data ingredients - use not supported (insufficient data or use not supported — CIR's own classification, not a full safety-as-used conclusion).
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 4845-99-2
- EC No.EU chemical inventory number
- 225-432-9
- DTXSIDUS EPA chemical ID
- DTXSID5052123
- DTXCIDUS EPA compound ID
- DTXCID7030692
- IUPAC
- Sulfuric acid--2,3-dimethoxystrychnidin-10-one (1/2)
- Molecular formula
- C46H54N4O12S
- Molecular weight
- 887.01 g/mol
Measured properties
- Appearance
- Off-white powder, [Sigma-Aldrich MSDS]
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Category 6.3B (Category 3)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
Linked databases 14
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata