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Ingredient Dictionary

BUTOXYDIGLYCOL

Ethanol, 2-(2-butoxyethoxy)- is an ether.

Molecular structure

Definition

Ethanol, 2-(2-butoxyethoxy)- is an ether.

Source: PubChem

US FDA substance register · UNII 9TB90IYC0E · registered name DIETHYLENE GLYCOL MONOBUTYL ETHER · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Base that dissolves other ingredientsSOLVENTAdjusts thicknessVISCOSITY CONTROLLINGListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Restricted
Taiwan · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)

Argentina · Brazil

  • Field of application and/or use : Solvent in hair dyes
  • Maximum concentration permitted at final product : 9%
  • Other limitations and requirements : Do not use in sprayable systems (aerosols and sprays)

ASEAN

  • Field of application and/or use : Solvent in hair dye products
  • Maximum authorised concentration in the finished cosmetic product : 9%
  • Other limitations and requirements : No use in aerosol dispensers (sprays)

European Union

  • Product Type, body parts : Solvent in hair dye products
  • Maximum concentration in ready for use preparation : 9%
  • Other : No use in aerosol dispensers (sprays)

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex III (restricted substances), entry 187 · maximum concentration 9% · applies to Solvent in hair dye products

Source: EU restricted substances (Annex III)

Restriction III/187 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ブトキシジグリコール: 本品は、次の化学式で表されるエーテルアルコールである。

Source: JCIA labelling names (Japan)

Names & identifiers

BUTOXYDIGLYCOLINCI부톡시다이글라이콜Korean label name (MFDS standard)Ethanol, 2-(2-butoxyethoxy)-SynonymブトキシジグリコールJapanese labelling name
CAS No.chemical registry number
112-34-5
EC No.EU chemical inventory number
203-961-6
DTXSIDUS EPA chemical ID
DTXSID8021519
DTXCIDUS EPA compound ID
DTXCID001519
IUPAC
2-(2-Butoxyethoxy)ethan-1-ol
Molecular formula
C8H18O3
Molecular weight
162.229 g/mol

Measured properties

Melting/freezing point
-68 ℃
Initial boiling point and range
231 ℃
Flash point
78 ℃(c.c.)
Upper/lower flammability or explosive limits
24.6 / 0.85 %
Vapour pressure
0.0219 ㎜Hg (25℃)
Water solubility
100 g/100㎖ (25℃)
Vapour density
5.6
Relative density
0.9553
n-Octanol/water partition coefficient (Kow)
0.56
Auto-ignition temperature
204 ℃
Viscosity
5.17 cSt
Molecular weight
162.26

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 250 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Solvent101
  • Solubility enhancer79
  • Cleaning agent11
  • Processing aids not otherwise specified9
  • No specific technical function7
  • Viscosity modifier5
  • Diluent4
  • Film former4
19 other uses
  • Chemical reaction regulator3
  • Stabilizing agent2
  • Pigment2
  • Dye2
  • Softener and conditioner2
  • Impregnation agent2
  • Fragrance2
  • Coalescing agent2
  • Deodorizer2
  • Corrosion inhibitor2
  • Catalyst1
  • Hydraulic fluids1
  • Anti-freeze agent1
  • Biocide1
  • Intermediate1
  • Defoamer1
  • Plasticizer1
  • Surface modifier1
  • Flow promoter1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

6 skin studies and 7 eye studies are on record.

Classed as moderate1Classed as low3

The studies disagree (the most common conclusion covers 25%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 13 studies
  • Moderate or Mild Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) May 12th, 1981 according to
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
  • Not classified
    Skin Irritation · Screening
  • Category 6.3B (Category 3)
    Skin Irritation · Read Across
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • Classification not possible
    Skin Sensitization · Screening
  • Moderate or Mild Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
  • Serious eye damage/eye irritation - Category 2A
    Eye Irritation · Screening
  • Eye Irrit. 2
    Eye Irritation · Authoritative
  • Severe Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
  • Eye irritation - category 2A
    Eye Irritation · Screening
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across
  • Category 2A
    Eye Irritation · Screening

Source: US EPA CompTox dashboard

Linked databases 25

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