Butyl Benzyl Phthalate can cause developmental toxicity according to The National Toxicology Program's Center for the Evaluation of Risks to Human Reproduction.
Definition
Butyl Benzyl Phthalate can cause developmental toxicity according to The National Toxicology Program's Center for the Evaluation of Risks to Human Reproduction.
Source: PubChem
US FDA substance register · UNII YPC4PJX59M · registered name BENZYL BUTYL PHTHALATE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · China · European Union · South Korea · Taiwan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)
Korea’s toxic-substance GHS classification: Danger · H400 (category 1) · H410 (category 1) · H360 (category 1B)
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1152
Restriction II/1152
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report on the Safety Assessment of Butyl Benzyl Phthalate
Reviewed by CIR: 40th Anniversary Overview and Rereview Summaries From 2011 to 2015
Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010
Reviewed by CIR: Re-evaluation: Dibutyl, Dimethyl and Diethyl Phthalate and Butyl Benzyl Phthalate
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 85-68-7
- EC No.EU chemical inventory number
- 201-622-7
- DTXSIDUS EPA chemical ID
- DTXSID3020205
- DTXCIDUS EPA compound ID
- DTXCID70205
- IUPAC
- Benzyl butyl benzene-1,2-dicarboxylate
- Molecular formula
- C19H20O4
- Molecular weight
- 312.365 g/mol
Measured properties
- Appearance
- Butyl benzyl phthalate appears as a clear colorless liquid with a mild odor. Primary hazard is to the environment. Immediate steps should be taken to limit spread to the environment. Easily penetrates the soil to contaminate groundwater and nearby waterways. · Liquid
- Odour
- Slight odor
- Boiling point
- 698 °F at 760 mmHg (NTP, 1992) · 370 °C
- Melting point
- less than -31 °F (NTP, 1992) · -35 °C
- Solubility
- less than 0.1 mg/mL at 72.5 °F (NTP, 1992) · In water, 2.69 mg/L at 25 °C
- Density
- 1.12 at 68 °F (USCG, 1999) - Denser than water, will sink · 1.119 g/cu cm at 25 °C
- Stability
- Stable under recommended storage conditions.
- Colour
- colourless
- Melting/freezing point
- &, lt, -35 ℃
- Initial boiling point and range
- 370 ℃
- Flash point
- 198 ℃
- Vapour pressure
- 1.1 ㎩(25℃)
- Water solubility
- 2.69 ㎎/ℓ(25℃)
- Relative density
- 1.1
- n-Octanol/water partition coefficient (Kow)
- 4.91 (log Pow, 20℃)
- Auto-ignition temperature
- 425 ℃
- Viscosity
- 42 mPa S
- Molecular weight
- 312.36
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 40 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Plasticizer35
- Viscosity modifier2
- Processing aids not otherwise specified2
- Sealant (barrier)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Not classified
Skin Irritation · Screening - Category 6.3B (Category 3)
Skin Irritation · Read Across - Classification not possible
Skin Sensitization · Screening - Not classified
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Bioaccumulation and trophic transfer of phthalate esters in mangrove food web. · 2025
- Measurement of phthalates in skin wipes: estimating exposure from dermal absorption. · 2014
- Butyl benzyl phthalate: effects on immune responses to ovalbumin in mice · 2009
- The Association between Phthalates in Dust and Allergic Diseases among Bulgarian Children · 2007
- Analysis of consumer cosmetic products for phthalate esters. · 2006
Linked databases 26
- AICIS inventory notices (Australia)
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- IARC carcinogen classification
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3 4 5
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports 2
- Wikidata
- Wikipedia · English · Japanese · Chinese