- Korean limit
- 2.5%
Definition
US FDA substance register · UNII H963NLD48W · registered name N-BUTYLDIETHANOLAMINE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted
- China · South Korea
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Field of application and/or use : (a) Products without rinse. (b) Other products.
- Maximum concentration permitted at final product : (a) 2.5%
- Other limitations and requirements : a.- b.- . No use with nitrosating systems . -Pureza minimum 99% maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor. 50 ug / kg -Envasar / keep in containers free of nitrites
ASEAN
- Field of application and/or use : (a) non-rinse-off products (b) other products
- Maximum authorised concentration in the finished cosmetic product : (a) 2.5%
- Other limitations and requirements : (a) (b): • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers
European Union
- Product Type, body parts : (a) Leave-on products (b) Rinse-off products
- Maximum concentration in ready for use preparation : (a) 2.5%
- Other : (a) (b) - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction III/62
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 102-79-4
- EC No.EU chemical inventory number
- 203-055-0
- DTXSIDUS EPA chemical ID
- DTXSID1044354
- DTXCIDUS EPA compound ID
- DTXCID9024354
- IUPAC
- 2,2'-(Butylazanediyl)di(ethan-1-ol)
- Molecular formula
- C8H19NO2
- Molecular weight
- 161.245 g/mol
Measured properties
- Appearance
- Liquid · Colorless to pale yellow liquid with a mild odor, [Taminco MSDS]
- Melting/freezing point
- -70 ℃
- Initial boiling point and range
- 262~290 ℃
- Flash point
- 118 ℃
- Upper/lower flammability or explosive limits
- 6.5 / 1.1 %
- Vapour pressure
- 0.000195 ㎜Hg (at 25℃(est.))
- Vapour density
- 5.55
- Relative density
- 0.96-1.0
- n-Octanol/water partition coefficient (Kow)
- -0.03 ((est.))
- Auto-ignition temperature
- 260 ℃
- Molecular weight
- 161.24
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- pH regulating agent1
- Intermediate1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 7 studies
- SkinIrr2
Skin Irritation · QSAR Predicted - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to other guideline: EEC Council directive 67/548/EEC, September 19, 1984 according to EPA OTS 798.4100 (Skin Sensitisation) - SkinSens1
Skin Sensitization · QSAR Predicted - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EPA OPPTS 870.2500 (Acute Dermal Irritation) according to - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) 1981 equivalent or similar to - Category 8.3A (Category 1)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 14
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata