Definition
US FDA substance register · UNII 61P3KJ8K4Y · registered name 2-ETHYL-2-BUTYL-1,3-PROPANEDIOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Reviewed by CIR: Safety Assessment of Alkane Diols as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ブチルエチルプロパンジオール: 本品は、次の化学式で表されるニ価アルコールである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 115-84-4
- EC No.EU chemical inventory number
- 204-111-7
- DTXSIDUS EPA chemical ID
- DTXSID8041400
- DTXCIDUS EPA compound ID
- DTXCID6021400
- IUPAC
- 2-Butyl-2-ethylpropane-1,3-diol
- Molecular formula
- C9H20O2
- Molecular weight
- 160.257 g/mol
Measured properties
- Colour
- white
- Melting/freezing point
- 44 ℃
- Initial boiling point and range
- 262 ℃
- Flash point
- 138 ℃
- Vapour pressure
- 0.0016 ㎜Hg (25 C)
- Relative density
- 0.929 ( at 50C)
- n-Octanol/water partition coefficient (Kow)
- 1.78
- Viscosity
- 208.00 cP (40 C)
- Molecular weight
- 160.26
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Humectant1
- Softener and conditioner1
- Processing aids not otherwise specified1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to EU Method B.6 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Severe Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Severe Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- Tlooto literature search
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata