Definition
US FDA substance register · UNII 4HZG7U1P1S · registered name BUTYLATED XYLENOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ブチル化キシレノール: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 1879-09-0
- EC No.EU chemical inventory number
- 217-533-1
- DTXSIDUS EPA chemical ID
- DTXSID6041551
- DTXCIDUS EPA compound ID
- DTXCID4021551
- IUPAC
- 2-tert-Butyl-4,6-dimethylphenol
- Molecular formula
- C12H18O
- Molecular weight
- 178.275 g/mol
Measured properties
- Appearance
- 2,4-dimethyl-6-tert-butyl phenol appears as a yellow liquid with a phenolic odor. Insoluble in water and about the same density as water. Exposure to skin, eyes or mucous membranes may cause severe burns. · Liquid, Other Solid
- Melting/freezing point
- 22.3 ℃
- Initial boiling point and range
- 248 ℃
- Flash point
- 111 ℃(c.c. @ 101 kPa)
- Flammability (solid, gas)
- flammable
- Vapour pressure
- 4.2 ㎩ (@ 25 ℃)
- Water solubility
- 29.6 ㎎/ℓ (@ 25 ℃, est.)
- Vapour density
- 6.15
- Relative density
- 0.967 (@ 20 ℃)
- n-Octanol/water partition coefficient (Kow)
- 3.64 (@ 35 ℃)
- Auto-ignition temperature
- 364 ℃
- Viscosity
- 50 cP (@ 20 ℃)
- Molecular weight
- 178.27
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Lubricating agent1
- Fuel1
- Stabilizing agent1
- Antioxidant1
- Catalyst1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
6 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Classification not possible
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - SkinSens1
Skin Sensitization · QSAR Predicted - SkinIrr2
Skin Irritation · QSAR Predicted - Classification not possible
Eye Irritation · Screening - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Category 8.3A (Category 1)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese