Definition
US FDA substance register · UNII 3IBO99KPV6 · registered name 2-BUTYLAMINOETHANOL · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction II/411 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 111-75-1
- EC No.EU chemical inventory number
- 203-904-5
- DTXSIDUS EPA chemical ID
- DTXSID9059410
- DTXCIDUS EPA compound ID
- DTXCID5033206
- IUPAC
- 2-(Butylamino)ethan-1-ol
- Molecular formula
- C6H15NO
- Molecular weight
- 117.192 g/mol
Measured properties
- Appearance
- liquid
- Colour
- colourless
- pH
- 11.9
- Melting/freezing point
- -2 ℃
- Initial boiling point and range
- 199 ℃
- Flash point
- 97.5 ℃(c.c.)
- Flammability (solid, gas)
- flammable
- Upper/lower flammability or explosive limits
- 1.5 / 8.6 %
- Vapour pressure
- 0.98 hPa (@ 50.85 ℃)
- Water solubility
- 1000000 ㎎/ℓ (@ 25 ℃)
- Vapour density
- 4.05
- Relative density
- 0.891 (@ 20 ℃)
- n-Octanol/water partition coefficient (Kow)
- 0.64 (@ 25 ℃)
- Auto-ignition temperature
- 300 ℃ (@ 988.3 hPa)
- Viscosity
- 19.7 cP (@ 20 ℃)
- Molecular weight
- 117.22
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Intermediate2
- pH regulating agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 7 studies
- Category 8.2C (Category 1C)
Skin Irritation · Read Across - Ambiguous
skin corrosion: in vitro / ex vivo · Screening · other guideline: OECD Guideline for Testing of Chemicals No. 431, April 13, 2004 ("In vitro Skin Corrosion: Human Skin Model Test") equivalent or similar to - Severe Irritation
skin irritation: in vivo · Screening · other guideline: Japan MAFF Testing Guideline of 12 Nousan No. 8147, adopted November 24, 2000 according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to EPA OPPTS 870.2500 (Acute Dermal Irritation) according to - SkinIrr2
Skin Irritation · QSAR Predicted - Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 8.3A (Category 1)
Eye Irritation · Read Across - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Linked databases 12
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata