Definition
US FDA substance register · UNII S9178G4B3F · registered name 3-BUTYLIDENEPHTHALIDE · mixture
Cosmetic roles
Gives the product a scentPERFUMING
More data — names, identifiers, properties, test records, literature
Names & identifiers
BUTYLIDENEPHTHALIDEINCI1(3H)-Isobenzofuranone, 3-butylidene-Synonym
- CAS No.chemical registry number
- 551-08-6
- EC No.EU chemical inventory number
- 208-991-3
- DTXSIDUS EPA chemical ID
- DTXSID9060281
- DTXCIDUS EPA compound ID
- DTXCID2041836
- IUPAC
- 3-Butylidene-2-benzofuran-1(3H)-one
- Molecular formula
- C12H12O2
- Molecular weight
- 188.226 g/mol
Measured properties
- Appearance
- clear, colorless liquid
- Colour
- colourless, clear
- Melting/freezing point
- -72 ℃(1013 hPa)
- Initial boiling point and range
- 232~239 ℃ (at 1013 hPa)
- Flash point
- 107 ℃(at 1013 hPa)
- Vapour pressure
- 0.5 ㎪ (at 100 °C)
- Water solubility
- 28.1 ㎎/ℓ (at 20 °C, pH 7)
- n-Octanol/water partition coefficient (Kow)
- 4.7
- Auto-ignition temperature
- 260 ℃ (1013 hPa)
- Viscosity
- 27.6 cSt (20 °C)
- Molecular weight
- 158.2811
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance3
- Flavouring and nutrient3
Source: US EPA CompTox dashboard
Related literature
- Resection and intracranial implant of (Z)- n -butylidenephthalide wafer followed by temozolomide as treatment for recurrent glioblastoma: A randomized phase IIb/III trial. · 2026
- Bioassay-guided isolation of insect repellent compounds from Ligusticum porteri root extract. · 2024
- Reduced psoriasis skin irritation symptoms through the effects of Chinese herbal medicines on planarians · 2024
- Targeting the Axl and mTOR Pathway Synergizes Immunotherapy and Chemotherapy to Butylidenephthalide in a Recurrent GBM · 2022
- Antitumor Effect of n-Butylidenephthalide Encapsulated on B16/F10 Melanoma Cells In Vitro with a Polycationic Liposome Containing PEI and Polyethylene Glycol Complex · 2018
Linked databases 14
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Chinese