Ingredient Dictionary

BUTYRALDEHYDE

Butanal is a member of the class of butanals that consists of propane bearing a formyl substituent at the 1-position.

Definition

Butanal is a member of the class of butanals that consists of propane bearing a formyl substituent at the 1-position. The parent of the class of butanals. It has a role as a biomarker, a mouse metabolite and an Escherichia coli metabolite.

Source: PubChem

US FDA substance register · UNII H21352682A · registered name Butyraldehyde · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

BUTYRALDEHYDEINCIButanalSynonym

CAS No.chemical registry number: 123-72-8
EC No.EU chemical inventory number: 204-646-6
DTXSIDUS EPA chemical ID: DTXSID8021513
DTXCIDUS EPA compound ID: DTXCID601513

IUPAC: Butanal
Molecular formula: C4H8O
Molecular weight: 72.107 g/mol

Measured properties

Appearance: liquid
Colour: colourless
Melting/freezing point: -99 ℃
Initial boiling point and range: 75~76 ℃
Flash point: -12 ℃(c.c.)
Upper/lower flammability or explosive limits: 12.5 / 1.9 %
Vapour pressure: 12.2 ㎪ (20℃)
Water solubility: 7.1 g/100㎖ (25℃)
Vapour density: 2.5
Relative density: 0.817
n-Octanol/water partition coefficient (Kow): 0.88
Auto-ignition temperature: 230 ℃
Molecular weight: 72.12

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 10 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance3
Flavouring and nutrient2
Monomers2
Solvent2
Intermediate1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

5 skin studies and 5 eye studies are on record.

Classed as low3

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 10 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) equivalent or similar to other guideline: method described by E.V Buehler in"Delayed Contact Hypersensitivity in teh Guinea Pig", Arch. Dermatol 91: 171-175 (1965)
Not classified
Skin Irritation · Screening
Category 6.3B (Category 3)
Skin Irritation · Read Across
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Classification not possible
Skin Sensitization · Screening
Serious eye damage/eye irritation - Category 2B
Eye Irritation · Screening
Severe Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Severe Irritation
eye irritation: in vivo · Screening · EPA OPP 81-4 (Acute Eye Irritation) according to
Category 2
Eye Irritation · Screening
Category 6.4A (Category 2A)
Eye Irritation · Read Across