Butyric acid is a straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
定义
Butyric acid is a straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group. It has a role as a Mycoplasma genitalium metabolite and a human urinary metabolite. It is a fatty acid 4:0 and a straight-chain saturated fatty acid. It is a conjugate acid of a butyrate.
来源: PubChem
美国FDA 物质登记 · UNII 40UIR9Q29H · 登记名称 Butyric Acid · 单一化学物质
化妆品中的作用
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 107-92-6
- EC No.欧盟化学品目录编号
- 203-532-3
- DTXSID美国EPA化学品编号
- DTXSID8021515
- DTXCID美国EPA化合物编号
- DTXCID401515
- IUPAC
- Butanoic acid
- 分子式
- C4H8O2
- 分子量
- 88.106 g/mol
实测物性
- 颜色
- 无色
- 熔点/凝固点
- -5 ℃
- 初沸点和沸程
- 164 ℃
- 闪点
- 72 ℃(c.c.)
- 燃烧或爆炸范围上限/下限
- 10 / 2 %
- 蒸气压
- 57 ㎩ (20℃)
- 溶解度
- 6 g/100㎖ (25℃)
- 蒸气密度
- 3
- 比重
- 0.964
- 正辛醇/水分配系数（Kow）
- 0.79
- 自燃温度
- 452 ℃
- 黏度
- 1.61 cP
- 分子量
- 88.12
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 22 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Fragrance8
- Flavouring and nutrient6
- pH regulating agent2
- Plasticizer1
- Monomers1
- Processing aids not otherwise specified1
- Intermediate1
- Antioxidant1
其余用途 1 项
- Deodorizer1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 7 项、眼部试验 2 项。
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 9 项试验
- Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 1981 according to - Classification not possible
Skin Sensitization · Screening - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Corrosive
skin irritation: in vivo · Screening · other guideline: DOT test; 19 CFR, Chapter I, Sec. 173.40 according to - Skin Corr. 1B
Skin Irritation · Authoritative - Category 1
Skin Irritation · Screening - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Category 1
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across
来源: 美国EPA CompTox
相关文献
- A new biocompatible butyric acid-releasing glucosamine derivative for transdermal delivery. · 2025
- Exploring the effect of butyric acid, a metabolite from periodontopathic bacteria, on primary human melanocytes: An in vitro study. · 2024
- Effects of butyric acid, a bacterial metabolite, on the migration of ameloblastoma mediated by laminin 332. · 2020
- Skin Cutibacterium acnes Mediates Fermentation to Suppress the Calcium Phosphate-Induced Itching: A Butyric Acid Derivative with Potential for Uremic Pruritus · 2020
- A Derivative of Butyric Acid, the Fermentation Metabolite of Staphylococcus epidermidis, Inhibits the Growth of a Staphylococcus aureus Strain Isolated from Atopic Dermatitis Patients · 2019