CAFFEINE

Caffeine is a trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee. It has a role as a geroprotector, a mutagen, a central nervous system stimulant, a psychotropic drug, a diuretic, a xenobiotic, an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor, an adenosine A2A receptor antagonist, an adjuvant, a food additive, a ryanodine receptor agonist, an adenosine receptor antagonist, a mouse metabolite, a plant metabolite, a fungal metabolite, an environmental contaminant and a human blood serum metabolite. It is a purine alkaloid and a trimethylxanthine.

来源: PubChem

美国FDA 物质登记 · UNII 3G6A5W338E · 登记名称 CAFFEINE · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

Caffeine is the heterocyclic organic compound that conforms to the formula

日本

• 每100g最大配合量 (Cosmetics not used for mucosa and to be washed away) : 2.0 g
• 每100g最大配合量 (Cosmetics not used for mucosa and not to be washed away) : 2.0 g
• 每100g最大配合量 (Cosmetics that may be used for mucosa) :

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息（环境公团）

Reviewed by CIR: Safety Assessment of Methylxanthines as Used in Cosmetics

来源: 美国CIR 安全性评估