Ingredient Dictionary

CALCIUM ACETATE

Calcium acetate is the calcium salt of acetic acid.

Definition

Calcium acetate is the calcium salt of acetic acid. It is used, commonly as a hydrate, to treat hyperphosphataemia (excess phosphate in the blood) in patients with kidney disease: the calcium ion combines with dietary phosphate to form (insoluble) calcium phosphate, which is excreted in the faeces. It has a role as a chelator. It contains an acetate.

Source: PubChem

US FDA substance register · UNII Y882YXF34X · registered name Calcium acetate · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Listed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCEAdjusts thicknessVISCOSITY CONTROLLING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Final Report of the Cosmetic Ingredient Reveiw Expert Panel on the Safety Assessment of Methyl Acetate

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name 酢酸Ｃａ: 本品は、酢酸（＊）のカルシウム塩であり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

CALCIUM ACETATEINCI칼슘아세테이트Korean label name (MFDS standard)Acetic acid, calcium salt (2:1)Synonym酢酸ＣａJapanese labelling name

CAS No.chemical registry number: 62-54-4
EC No.EU chemical inventory number: 200-540-9
DTXSIDUS EPA chemical ID: DTXSID0020234
DTXCIDUS EPA compound ID: DTXCID00234

IUPAC: Calcium diacetate
Molecular formula: C4H6CaO4
Molecular weight: 158.166 g/mol

Measured properties

Appearance: Large Crystals, CBI, Dry Powder, Other Solid, Liquid · Anhydrous calcium acetate is a white, hygroscopic, bulky, crystalline solid with a slightly bitter taste. A slight odour of acetic acid may be present. The monohydrate may be needles, granules or powder
Odour: SLIGHT ODOR OF ACETIC ACID
Melting point: > 160 °C
Solubility: 37.4 G IN 100 CC OF WATER @ 0 °C, 29.7 G IN 100 CC OF WATER @ 100 °C, SLIGHTLY SOL IN ALCOHOL · Practically insol in acetone and benzene
Density: 1.50 kg/l · 1.5 g/cm³
Stability: VERY HYGROSCOPIC ...
pH: 6,0-9,0 (10 % aqueous solution) · 0.2 molar aq soln: 7.6 /Monohydrate form/
Flammability (solid, gas): combustible
Vapour pressure: 0.005 ㎜Hg (at 25℃)
Water solubility: 400000 ㎎/ℓ
Vapour density: 5.46
Relative density: 1.50
n-Octanol/water partition coefficient (Kow): -1.38
Auto-ignition temperature: 340 ℃
Decomposition temperature: 160 ℃
Molecular weight: 158.17

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 24 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Thickening agent5
Lubricating agent3
Stabilizing agent3
Processing aids not otherwise specified2
Preservative2
Filler2
Chelating agent1
Viscosity modifier1

5 other uses

pH regulating agent1
Dye1
Flavouring and nutrient1
Anti-freeze agent1
Deodorizer1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to