Calcium citrate is an organic calcium salt composed of calcium cations and citrate anions in a 3:2 ratio.
Definition
Calcium citrate is an organic calcium salt composed of calcium cations and citrate anions in a 3:2 ratio. It has a role as a flavouring agent, a nutraceutical, a food additive and a food preservative. It contains a citrate(3-).
Source: PubChem
US FDA substance register · UNII 86117BWO7P · registered name CALCIUM CITRATE ANHYDROUS · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Safety Assessment of Citric Acid, Inorganic Citrate Salts, and Alkyl Citrate Esters as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name クエン酸Ｃａ: 本品は、クエン酸（＊）のカルシウム塩である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 5785-44-4
- CAS No.chemical registry number
- 813-94-5
- EC No.EU chemical inventory number
- 212-391-7
- DTXSIDUS EPA chemical ID
- DTXSID7061148
- DTXCIDUS EPA compound ID
- DTXCID5048215
- IUPAC
- Calcium 2-hydroxypropane-1,2,3-tricarboxylate (3/2)
- Molecular formula
- C12H10Ca3O14
- Molecular weight
- 498.432 g/mol
Measured properties
- Colour
- white
- Melting/freezing point
- 317.63 ℃
- Initial boiling point and range
- 724.86 ℃
- n-Octanol/water partition coefficient (Kow)
- (-4.79)
- Molecular weight
- 498.44
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- pH regulating agent2
- Flavouring and nutrient1
- Stabilizing agent1
- Chelating agent1
- Processing aids not otherwise specified1
Source: US EPA CompTox dashboard
Related literature
- Targeted Therapy with Cisplatin-Loaded Calcium Citrate Nanoparticles Conjugated with Epidermal Growth Factor for Lung Cancer Treatment · 2024
- The effects of alpha-lipoic acid transdermal patch for local subcutaneous fat reduction: A randomized, placebo-controlled, clinical trial in overweight volunteers · 2024
- Development of Eugenol-Embedded Calcium Citrate Nanoparticles as a Local Anesthetic Agent · 2021
- Allergic reaction to platelet-rich plasma (PRP) · 2019
- Extended shelf-life of ‘Kumhong’ nectarine and ‘Madoka’ peach fruits by treating the trees with calcium compounds and chitosan · 2019
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese