Calcium oxide is a member of the class of calcium oxides of calcium and oxygen in a 1:1 ratio.
Definition
Calcium oxide is a member of the class of calcium oxides of calcium and oxygen in a 1:1 ratio. It has a role as a fertilizer.
Source: PubChem
US FDA substance register · UNII C7X2M0VVNH · registered name LIME (CALCIUM OXIDE) · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 酸化Ca: 本品は、カルシウムの酸化物であり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 1305-78-8
- EC No.EU chemical inventory number
- 215-138-9
- DTXSIDUS EPA chemical ID
- DTXSID5029631
- DTXCIDUS EPA compound ID
- DTXCID101323191
- IUPAC
- Calcium oxide
- Molecular formula
- CaO
- Molecular weight
- 56.077 g/mol
Measured properties
- Appearance
- Calcium oxide appears as an odorless, white or gray-white solid in the form of hard lumps. A strong irritant to skin, eyes and mucous membranes. Used in insecticides and fertilizers. · Dry Powder, Wet Solid, Other Solid, Large Crystals, CBI, Liquid
- Odour
- Odorless · odourless
- Boiling point
- 5162 °F at 760 mmHg (NIOSH, 2024) · 2850 °C
- Melting point
- 4662 °F (NIOSH, 2024) · 2613 °C
- Solubility
- Reacts with water (NIOSH, 2024) · Slightly soluble in water. Insoluble in ethanol. Soluble in glycerol
- Density
- 3.3 at 68 °F (USCG, 1999) - Denser than water, will sink · 3.34 g/cu cm
- Stability
- Readily absorbs carbon dioxide and water from air, becoming airslaked.
- Colour
- white
- pH
- 12.8
- Melting/freezing point
- 2570 ℃
- Initial boiling point and range
- 2850 ℃
- Relative density
- 3.3-3.4
- Molecular weight
- 56.1
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 111 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Binder35
- Processing aids not otherwise specified12
- Degradant/impurity (EPA)8
- pH regulating agent7
- Filler6
- Stabilizing agent4
- Chemical reaction regulator4
- Intermediate4
19 other uses
- Catalyst3
- Dehydrating agent (desiccant)3
- Drier3
- Corrosion inhibitor2
- Sealant (barrier)2
- Abrasive2
- Flux agent2
- Diluent2
- Soil amendments2
- Thickening agent1
- Viscosity modifier1
- Adhesion/cohesion promoter1
- Adsorbent1
- Absorbent1
- Dye1
- Flavouring and nutrient1
- Anti-caking agent1
- Reducing agent1
- Dispersing agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
8 skin studies and 5 eye studies are on record.
The studies disagree (the most common conclusion covers 17%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 13 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) , adopted 1992-07-17 according to - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Category 2
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Skin irritation - category 2
Skin Irritation · Screening - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) , adopted 1987-02-24 according to - Category 1
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Eye damage - category 1
Eye Irritation · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
- Eggshell-derived calcium oxide nanoparticles as promising anti-cancer agent: synthesis, characterization and in-vitro evaluation · 2025
- Efficient biogenesis of calcium oxide nanoparticles using the extract of Eleusine coracana seeds and their application against multidrug-resistant ocular bacterial pathogens. · 2024
- Practical effect of calcium oxide and sodium chloride on the control and treatment of Ichthyophthirius multifiliis in Gold fish (Carassius auratus) farms · 2020
- Development of in situ gels of nano calcium oxide for healing of burns · 2020
- Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes · 2020
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese