Calcium diphosphate is a calcium phosphate.
定义
Calcium diphosphate is a calcium phosphate. It contains a diphosphate(4-).
来源: PubChem
美国FDA 物质登记 · UNII X69NU20D19 · 登记名称 CALCIUM PYROPHOSPHATE · 单一化学物质
化妆品中的作用
护理口腔ORAL CARE防止光照导致颜色和香味变化LIGHT STABILIZER物理摩擦清洁ABRASIVE
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
Reviewed by CIR: Safety Assessment of Phosphoric Acid and Its Salts as Used in Cosmetics
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 リン酸（Ｃａ／セリウム）: 本品は、炭酸Ｃａ（＊）、ピロリン酸カルシウム及びセリウムの焼成物である。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
CALCIUM PYROPHOSPHATEINCI칼슘파이로포스페이트韩国标示名称（食药处标准名）Diphosphoric acid, calcium salt (1:2)同义名CALCIUM CERIUM PHOSPHATE同义名
- CAS No.化学物质登记号
- 7790-76-3
- EC No.欧盟化学品目录编号
- 232-221-5
- DTXSID美国EPA化学品编号
- DTXSID50872512
- DTXCID美国EPA化合物编号
- DTXCID40820163
- IUPAC
- Dicalcium diphosphate
- 分子式
- Ca2O7P2
- 分子量
- 254.097 g/mol
实测物性
- 性状
- Dry Powder · A fine, white, odourless powder
- 熔点
- 1353 °C
- 溶解性
- Insoluble in water. Soluble in dilute hydrochloric and nitric acids · Sol in dil hydrochloric and nitric acids, practically insol in water
- 密度
- 3.09
- pH
- Between 5,5 and 7,0 (10 % suspension in water)
- 颜色
- 白色
- 熔点/凝固点
- 1353 ℃
- 比重
- 3.09
- 分子量
- 254.10
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 6 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Abrasive3
- Filler1
- Flavouring and nutrient1
- Stabilizing agent1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 2 项、眼部试验 4 项。
归类为低2 项
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 6 项试验
- Studies Indicate No Significant Irritation
skin corrosion: in vitro / ex vivo · Screening · EU Method B.46 (In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test) according to OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) 2012 according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Ambiguous
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to EU method B.47 (Bovine corneal opacity and permeability test method for identifying ocular corrosives and severe irritants) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
来源: 美国EPA CompTox
相关文献
- P028 Crowned dens syndrome: a rare yet important-to-recognise phenotype of calcium pyrophosphate crystal deposition disease · 2025
- Concurrent Post-Zoster Cutaneous Vasculitis and Acute Calcium Pyrophosphate Deposition Disease (CPPD) in an Elderly Patient: A Case Report · 2024
- THU0419 BIOLOGICS IN THE TREATMENT OF CALCIUM PYROPHOSPHATE DEPOSITION DISEASE. A SYSTEMATIC LITERATURE REVIEW · 2020
- Acute calcific tendinitis of gluteus maximus tendon due to tumoral calcium pyrophosphate dihydrate deposition disease · 2017
- Coincidence of monosodium urate monohydrate, calcium pyrophosphate dihydrate, and basic calcium phosphate crystals in the synovial fluid from a single joint · 2016