Calcium sulfide is an organic molecular entity.
Definition
US FDA substance register · UNII 1MBW07J51Q · registered name CALCIUM SULFIDE · single chemical substance
Calcium sulfide is an organic molecular entity.
Source: PubChem
Cosmetic roles
Safety & regulatory references
- Restricted or banned
- South Korea
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Field of application and/or use : (a) (b) and Depilatories
- Maximum concentration permitted at final product : a.- 2% calculated as sulfur pH up to 12.7 b.- 6% calculated as sulfur pH to 12.7
- Use conditions and warnings that must appear on the label : a.- b.- and Keep out of the reach of children. Avoid contact with eyes.
ASEAN
- Field of application and/or use : (a) Depilatories (b) Depilatories
- Maximum authorised concentration in the finished cosmetic product : (a) 2% calculated as sulphur pH up to 12.7 (b) 6% calculated as sulphur pH up to 12.7
- Conditions of use and warning which must be printed on the labels : (a) • Keep out of reach of children • Avoid contact with eyes (b) • Keep out of reach of children • Avoid contact with eyes
Canada
- Conditions of Use by product type : In hair removal (depilatory) products
- Maximum Concentration Permitted : 6% as sulfur
European Union
- Product Type, body parts : (a) Depilatories (b) Depilatories
- Maximum concentration in ready for use preparation : (a) 2% (as sulphur) (b) 6% (as sulphur)
- Other : pH<=12.7
- Wording of conditions of use and warnings : (a) (b) Keep out of reach of children Avoid contact with eyes
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction III/23 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 20548-54-3
- EC No.EU chemical inventory number
- 243-873-5
- DTXSIDUS EPA chemical ID
- DTXSID30885140
- DTXCIDUS EPA compound ID
- DTXCID901024539
- IUPAC
- Calcium sulfide
- Molecular formula
- CaS
- Molecular weight
- 72.14 g/mol
Measured properties
- Appearance
- White solid when pure, Crude and luminous forms may be yellowish to pale-grey, Odor of hydrogen sulfide in moist air, [Merck Index] Colorless powder with an odor of rotten eggs, [Alfa Aesar MSDS]
- Melting point
- 2524 °C
- Density
- 2.58 @25 °C
- Colour
- colourless
- Melting/freezing point
- 2450 ℃
- Relative density
- 2.59
- Molecular weight
- 72.14
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Depilatory (EPA)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Skin Irrit. 2
Skin Irritation · Authoritative - Category 6.3A (Category 2)
Skin Irritation · Read Across - Eye Irrit. 2
Eye Irritation · Authoritative - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Calcium Sulfide Nanoclusters Trigger DNA Damage and Induce Cell Cycle Arrest in Non-Small-Cell Lung Adenocarcinoma Cells · 2025
- Analytical acknowledgment of the kinetics of modifications of non-metal inclusions in the process of treatment of steel with calcium · 2024
- A Computational Study of the Dissociation of CaS Nanoclusters in the Extracellular Fluid of Cancer Cells: the Effect of pH in the Structure and Stability of Protonated CaS Nanoclusters · 2022
- Cadmium Sulfide · 2020
- Effect of CaS nanostructures in growth and proliferation of melanoma and benign skin cells in vitro · 2019
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- Health Canada Cosmetic Ingredient Hotlist
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese