Definición
Registro de sustancias de la FDA (EE. UU.) · UNII J96129652N · nombre registrado CALCIUM THIOGLYCOLATE · sustancia química única
Fuente: Identificador único de ingredientes de la FDA (UNII)
Funciones cosméticas
Referencias de seguridad y regulación
- Restringido
- Corea del Sur
Fuente: Información regulatoria cosmética del MFDS (Corea)
Argentina · Brasil
- Field of application and/or use : (a) Products for hair straightening or waving: 1. General use 2. Professional use (b) Depilatories (c) Other products for hair care which are removed after application
- Maximum concentration permitted at final product : (a) 1. 8% ready to use pH 7 to 9.5 2. 11% ready to use pH 7 to 9.5 (b) 5% ready to use pH 7 to 12.7 (c) 2% .ready to use pH 7 to 9.5 The indicated percentages are calculated as thioglycolic acid
- Other limitations and requirements : a, b and c) In the USAGE must obligatorily the following information recorded: - Avoid contact with eyes. - In case of contact with eyes, rinse immediately with plenty water and consult a doctor - and c) Wear suitable gloves
- Use conditions and warnings that must appear on the label : a), b) and c) - Contains thioglycolic acid salts - Follow instructions - Keep out of reach of children - Only for professional use (where appropriate)
ASEAN
- Field of application and/or use : (a) Hair waving or straightening products: 1. General use 2. Professional use (b) Depilatories (c) Other hair care products which are removed after application
- Maximum authorised concentration in the finished cosmetic product : (a) 1. 8% ready for use at pH 7 – 9.5 2. 11% ready for use at pH 7- 9.5 (b) 5% ready for use at pH 7-12.7 (c) 2% ready for use at pH 7-9.5 For general use of hair waving or straightening products the maximum concentration for combination of Thioglycolic acid and thiolactic acid must not exceed 8% calculated as Thioglycolic Acid.
- Other limitations and requirements : (a) (b) (c) The directions for use drawn up in the national or official language(s) must obligatorily incorporate the following sentences: • Avoid contact with eyes • In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice. • Wear suitable gloves (a) and (c) only.
- Conditions of use and warning which must be printed on the labels : (a) • Contains thioglycolate • Follow the instructions • Keep out of reach of children. • For professional use only. (b) and (c) • Contains thioglycolate • Follow the instructions • Keep out of reach of children
Canadá
- Conditions of Use by product type : (a) Eyelash curling products (b) Hair dyes, waving or straightening products (c) Hair dyes, waving or straightening products for professional use (d) Depilatory products
- Maximum Concentration Permitted : ((a) 11% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (b) 8% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (c) 11% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (d) 5% (as thioglycolic aci(d) with a pH less than or equal to 12.7
- Warnings and Cautionary Statements: (to the effect of) : (a) "For professional use only.", "Avoid direct skin contact, wear suitable gloves.", "Avoid contact with eyes and, in the event of contact with eyes, rinse immediately with plenty of water and seek medical attention." (b)"Avoid direct skin contact, wear suitable gloves.", "Not for use in the area of the eye." (c) "For professional use only." "Avoid direct skin contact, wear suitable gloves.", "Not for use in the area of the eye." d) "Avoid contact with eyes and, in the event of contact with eyes, rinse immediately with plenty of water and seek medical attention."
China
- Concentración máxima : (a)
Unión Europea
- Product Type, body parts : (a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
- Maximum concentration in ready for use preparation : (a) 1) 8% 2) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
- Other : (a) General use ready for use pH 7 to 9.5 Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5
- Wording of conditions of use and warnings : Condition of use: (a) (b) (c) Avoid contact with eyes In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a) (d) For professional use only: Cotains thiglycolata, folow the instruction.
Fuente: Información regulatoria cosmética del MFDS (Corea)
Restriction III/2a · Other restriction: ban substances that deplete the ozone layer
Reviewed by CIR: Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid
Más datos: nombres, identificadores, propiedades, ensayos y literatura
Nombres y definiciones oficiales
Nombre de etiquetado de la JCIA チオグリコール酸Ca: 本品は、チオグリコール酸(*)のカルシウム塩であり、次の化学式で表される。
Nombres e identificadores
- CAS No.número de registro químico
- 65208-41-5
- CAS No.número de registro químico
- 814-71-1
- CAS No.número de registro químico
- 5793-98-6
- EC No.número de inventario químico de la UE
- 249-881-5
- EC No.número de inventario químico de la UE
- 212-402-5
- DTXSIDidentificador químico de la EPA (EE. UU.)
- DTXSID6061151
- DTXCIDidentificador de compuesto de la EPA (EE. UU.)
- DTXCID5048219
- IUPAC
- Calcium bis(sulfanylacetate)
- Fórmula molecular
- C4H6CaO4S2
- Peso molecular
- 222.29 g/mol
Propiedades medidas
- Aspecto
- sólido
- Color
- blanco
- pH
- 11-12
- Punto de fusión/congelación
- 220 ℃
- Punto inicial e intervalo de ebullición
- 259.97 ℃
- Presión de vapor
- 0.0159 ㎜Hg
- Solubilidad en agua
- 323150 ㎎/ℓ
- Coeficiente de reparto n-octanol/agua (Kow)
- -2.490
- Peso molecular
- 222.30
Valores medidos en la sustancia en sí. Los datos de KOSHA son una referencia para redactar y revisar fichas de seguridad, no una especificación de una materia prima comercial.
Para qué lo usan los productos
Usos de los 15 productos declarados ante la EPA de EE. UU. con este ingrediente. Incluye productos que no son cosméticos, así que las primeras filas son sus usos principales.
- Depilatory (EPA)10
- Reducing agent2
- Pharmaceutical (EPA)2
- Abrasive1
Fuente: Panel CompTox de la EPA
Estudios de irritación y sensibilización
Constan 3 estudios en piel y 1 en ojos.
Las conclusiones de los estudios coinciden en general (100%). Son ensayos de la materia prima en sí; la irritación a la cantidad de un producto terminado es otra cuestión.
Ver los 4 estudios
- Skin sensitisation - category 1
Skin Sensitization · Screening - SkinSens1
Skin Sensitization · QSAR Predicted - Skin irritation - category 2
Skin Irritation · Screening - Eye irritation - category 2A
Eye Irritation · Screening
Fuente: Panel CompTox de la EPA
Literatura relacionada
- A Comparative Assessment of the Quality of Milk-Validation of Standard Brands versus Local Milk Sold in Market · 2018
- Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thio · 2009
- Enhancing effect of absorption promoters on percutaneous absorption of a model dye (6-carboxyfluorescein) as a poorly absorbable drug. III. Histological study after addition of various absorption promoters in rats. · 1986
- Absorption of indomethacin and its calcium salt through rat skin: effect of penetration enhancers and relationship between in vivo and in vitro penetration. · 1986
Bases de datos vinculadas 16
- Base de datos química DSSTox de la EPA
- Búsqueda bibliográfica Tlooto 2 3 4
- Cosmetic Ingredient Review (CIR, EE. UU.) 2
- Diccionario de ingredientes de la Asociación Coreana de Cosméticos
- Fichas de datos de seguridad de KOSHA (Corea)
- Identificador único de ingredientes de la FDA (UNII)
- Identificadores cruzados UniChem
- Información regulatoria cosmética del MFDS (Corea) 2 3
- Inventario de ingredientes de China (IECIC)
- Inventario de productos químicos de Australia (AICIS)
- Lista de ingredientes CosIng (UE) 2
- Nombres de etiquetado de la JCIA (Japón)
- Panel CompTox de la EPA 2
- Registro de ingredientes cosméticos del MFDS (Corea) 2
- Registro de sustancias de la FDA (GSRS)
- Wikidata