Ingredient Dictionary

CAPRYLOYL GLYCINE

N-octanoylglycine is an N-acylglycine that has octanoyl as the acyl group.

How much products actually contain

No product states its amount yet.

Of the products containing it, 25 list it before the 1% line and 29 after it (usually 1% or less).

Products using this ingredient

12 of 54 confirmed · likeliest to carry enough first · See all 54

Definition

N-octanoylglycine is an N-acylglycine that has octanoyl as the acyl group. It has a role as a metabolite. It is a N-acylglycine and a fatty amide. It is functionally related to a glycine and an octanoic acid. It is a conjugate acid of a N-octanoylglycinate.

Source: PubChem

US FDA substance register · UNII 8TY5YO42NJ · registered name CAPRYLOYL GLYCINE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Capryloyl Glycine is the acylation product of glycine with caprylic acid chloride. It conforms to the formula:

Cosmetic roles

Inhibits microbial growthANTIMICROBIALReduces body odourDEODORANTSurfactant that lifts dirtSURFACTANT - CLEANSINGActs on seborrheic flaking and dandruffANTI-SEBORRHEICReduces sebum productionANTI-SEBUMSoftens hairHAIR CONDITIONING

Safety & regulatory references

Reviewed by CIR: Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name カプリロイルグリシン: 本品は、グリシン（＊）のカプリル酸アミドであり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

CAPRYLOYL GLYCINEINCI카프릴로일글라이신Korean label name (MFDS standard)Glycine, N-(1-oxooctyl)-SynonymカプリロイルグリシンJapanese labelling name

CAS No.chemical registry number: 14246-53-8
EC No.EU chemical inventory number: 238-122-3
DTXSIDUS EPA chemical ID: DTXSID9065736
DTXCIDUS EPA compound ID: DTXCID1034638

IUPAC: N-Octanoylglycine
Molecular formula: C10H19NO3
Molecular weight: 201.266 g/mol

Measured properties

Appearance: Solid

Values measured on the substance itself, not a specification for a commercial raw material.

Source: PubChem

What products actually use it for

What the 10 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Cleaning agent4
Softener and conditioner3
Surfactant (surface active agent)3

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as highly irritating1Classed as low1

The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: BIOGIR SA Protocole SMK
Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to