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Ingredients

Ingredient Dictionary

CAPRYLYL METHICONE

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 627 list it before the 1% line and 50 after it (usually 1% or less).

Products using this ingredient

12 of 649 confirmed · likeliest to carry enough first · See all 649

Definition

US FDA substance register · UNII Q95M2P1KJL · registered name CAPRYLYL TRISILOXANE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Final Report: Safety Assessment of Dimethicones, Methicone and Substituted-Methicone Polymers as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name カプリリルメチコン: 本品は、次の化学式で表されるシリコーン重合体である。

Source: JCIA labelling names (Japan)

Names & identifiers

CAPRYLYL METHICONEINCI카프릴릴메티콘Korean label name (MFDS standard)Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-3-octyl-SynonymCAPRYLYL TRISILOXANESynonymカプリリルメチコンJapanese labelling name
CAS No.chemical registry number
17955-88-3
EC No.EU chemical inventory number
241-881-3
DTXSIDUS EPA chemical ID
DTXSID6051807
DTXCIDUS EPA compound ID
DTXCID6030362
IUPAC
1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane
Molecular formula
C15H38O2Si3
Molecular weight
334.722 g/mol

What products actually use it for

What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Softener and conditioner6
  • Humectant1
  • Solvent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 3 eye studies are on record.

Classed as low5

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 7 studies
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) 1992
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 1992 according to other guideline: Commission Directive 92/69/EEC, Annex Part B, Method B4 Acute Toxicity (Skin Irritation) according to other guideline: US EPA: OPPTS 870.2500, Health Effects Test Guidelines: Acute Dermal Irritation, August 1998 according to
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to other guideline: EPA (TSCA) Test Guidelines (Federal Register Vol. 50, No. 188) according to
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • Studies Indicate No Significant Irritation
    eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) 1987 according to other guideline: Commission Directive 92/69/EEC, Annex Part B, Method B5 Acute Toxicity (Eye Irritation) according to other guideline: US EPA: OPPTS 870.2400, Health Effects Test Guidelines, Acute Eye Irritation according to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to other guideline: EPA (TSCA) Test Guidelines (Federal Register Vol. 50, No. 188) according to

Source: US EPA CompTox dashboard

Linked databases 14