N-Octyl-2-pyrrolidone is a N-alkylpyrrolidine.
Definition
N-Octyl-2-pyrrolidone is a N-alkylpyrrolidine.
Source: PubChem
US FDA substance register · UNII N8YJ26SB8V · registered name Caprylyl Pyrrolidone · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name カプリリルピロリドン: 本品は、次の化学式で表される複素環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 2687-94-7
- EC No.EU chemical inventory number
- 403-700-8
- DTXSIDUS EPA chemical ID
- DTXSID4036435
- DTXCIDUS EPA compound ID
- DTXCID2016435
- IUPAC
- 1-Octylpyrrolidin-2-one
- Molecular formula
- C12H23NO
- Molecular weight
- 197.322 g/mol
Measured properties
- Appearance
- Liquid · Colorless viscous liquid, [Aldrich MSDS]
- Colour
- colourless
- Flash point
- &, gt, 109 ℃
- Relative density
- 0.92~0.921g/cm3
- n-Octanol/water partition coefficient (Kow)
- 3.33 (est.)
- Molecular weight
- 197.36
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 15 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Surfactant (surface active agent)4
- Solubility enhancer4
- Solvent3
- Soil amendments1
- Wetting agent (non-aqueous)1
- Plasticizer1
- Intermediate1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
6 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Skin Corr. 1B
Skin Irritation · Authoritative - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Corrosive
skin irritation: in vivo · Screening · other guideline: modification of that described by J.H. Draize. according to - Corrosive
skin irritation: in vivo · Screening · other guideline: US DOT requirement 49 CFR 173.1200 according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: modification of that described by J.H. Draize equivalent or similar to - Category 8.3A (Category 1)
Eye Irritation · Read Across - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: modification of that described by J.H. Draize. according to - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: modification of that described by J.H. Draize. according to
Source: US EPA CompTox dashboard
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata