S-carboxymethyl-L-cysteine is an L-cysteine thioether that is L-cysteine in which the hydrogen of the thiol group has been replaced by a carboxymethyl group.
How much products actually contain
No product states its amount yet.
Of the products containing it, 0 list it before the 1% line and 3 after it (usually 1% or less).
Products using this ingredient
3 of 3 confirmed · likeliest to carry enough first
Definition
S-carboxymethyl-L-cysteine is an L-cysteine thioether that is L-cysteine in which the hydrogen of the thiol group has been replaced by a carboxymethyl group. It has a role as a mucolytic. It is a L-cysteine thioether and a non-proteinogenic L-alpha-amino acid. It is a conjugate acid of a S-carboxylatomethyl-L-cysteine(1-).
Source: PubChem
US FDA substance register · UNII 740J2QX53R · registered name CARBOCYSTEINE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name カルボシステイン: 本品は、次の化学式で表される置換アミノ酸である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 638-23-3
- EC No.EU chemical inventory number
- 211-327-5
- DTXSIDUS EPA chemical ID
- DTXSID30110060
- DTXCIDUS EPA compound ID
- DTXCID3065320
- IUPAC
- S-(Carboxymethyl)-L-cysteine
- Molecular formula
- C5H9NO4S
- Molecular weight
- 179.19 g/mol
Measured properties
- Boiling point
- 417.3 ± 45.0
- Melting point
- 185-187
- Solubility
- 1.6g/L
- Dissociation constant
- 1.84
- Colour
- white
- Melting/freezing point
- 204~207 ℃
- Initial boiling point and range
- 359 ℃
- Vapour pressure
- 0.000000152 ㎜Hg (@ 25 °C)
- Water solubility
- 1000000 ㎎/ℓ
- n-Octanol/water partition coefficient (Kow)
- -4.24
- Molecular weight
- 179.21
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Pharmaceutical (EPA)1
- Softener and conditioner1
Source: US EPA CompTox dashboard
Related literature
- Avaliação das propriedades das fibras capilares tratadas com alisante ácido com diferentes valores de pH · 2019
- Treatment and management strategies of onychomycosis. · 2020
- Case Report: Kawasaki disease associated with acute generalized exanthematous pustulosis secondary to carbocysteine · 2024
- Development of a carbocysteine 10% + urea 5% cream for the topical treatment of congenital ichthyosis. · 2022
- Patch testing with methylchloroisothiazolinone/methylisothiazolinone—Comparison of results with TRUE Test and 200 ppm aq., and methylisothiazolinone patch test outcome · 2020
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese