CARNOSIC ACID
Carnosic acid is an abietane diterpenoid that is abieta-8,11,13-triene substituted by hydroxy groups at positions 11 and 12 and a carboxy group at position 20.
定義
Carnosic acid is an abietane diterpenoid that is abieta-8,11,13-triene substituted by hydroxy groups at positions 11 and 12 and a carboxy group at position 20. It is isolated from rosemary (Rosmarinus officinalis) and common sage (Salvia officinalis) and exhibits anti-angiogenic, antineoplastic, antioxidant and anti-HIV activity. It has a role as an antioxidant, an antineoplastic agent, a HIV protease inhibitor, an angiogenesis modulating agent, a food preservative, an anti-inflammatory agent, an apoptosis inducer and a plant metabolite. It is a monocarboxylic acid, a member of catechols, an abietane diterpenoid and a carbotricyclic compound. It is a conjugate acid of a carnosate.
出典: PubChem
米国FDA 物質登録 · UNII LI791SXT24 · 登録名 CARNOSIC ACID · 単一の化学物質
化粧品での役割
安全性・規制情報
Other restriction: ban substances that deplete the ozone layer
出典: EU CosIng 成分リスト
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
公式表示名・定義
日本化粧品工業会の表示名称 カルノシン酸: 本品は、次の化学式で表される環式化合物である。
出典: 日本化粧品工業会 表示名称
別名・識別情報
- CAS No.化学物質登録番号
- 3650-09-7
- DTXSID米国EPA化学物質番号
- DTXSID20904450
- DTXCID米国EPA化合物番号
- DTXCID601333604
- IUPAC
- 11,12-Dihydroxyabieta-8,11,13-trien-20-oic acid
- 分子式
- C20H28O4
- 分子量
- 332.44 g/mol
製品が実際に使っている用途
関連文献
- Inhibitory Effects of Carnosic Acid on Melanin Synthesis · 2022
- rehalose and carnosic acid induced LC3I, LC3II ratio, P62 down-regulation and cleaved caspase 3 expression in neural stem cells. · 2022
- Therapeutic Potential of Carnosic Acid in Alopecia: A Mechanistic Perspective · 2025
- Naturally-occurring carnosic acid as a promising therapeutic agent for skin inflammation via targeting STAT1. · 2025
- The cumulative effect of ellagic acid and carnosic acid attenuates oxidative events during diabetic wound healing: in different applications and on different days · 2024