Carnosine is a dipeptide that is the N-(beta-alanyl) derivative of L-histidine.
How much products actually contain
13 products state the amountmedian 0.07%
- under 0.01% 4
- 0.01–0.1% 9
- 0.1–1% 0
- 1% or more 0
Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.
Of the products containing it, 42 list it before the 1% line and 124 after it (usually 1% or less).
Products using this ingredient
12 of 166 confirmed · likeliest to carry enough first · See all 166
BENTONBenton Guava Moisture Soothing Serum
Peace Out SkincarePeace Out Skincare Peace Out Wrinkles
Elizabeth ArdenElizabeth Arden PREVAGE® Antioxidant Infusion Essence
ESTHEDERMCellular Water Essence 125ml (Bubble Essence)
ESTHEDERMCellular Water Essence 125ml
REJURANActive Cream Enhanced
MEDIPEELMEDIPEEL EGF Scaling Moisture Bubble Foot Shampoo 400ml
A'demangAnti-Glycation AGEs Deep Protect Care 6K Ampoule
La Roche-PosayMela B3 Serum 30ml
HERAUV Protector Tone-Up Lavender (SPF50
LAYERLABMelasma Marks Clear Serum 30ml
HERARetinol 3X Lifting Serum
Definition
Carnosine is a dipeptide that is the N-(beta-alanyl) derivative of L-histidine. It has a role as a geroprotector, an antioxidant, an antineoplastic agent, an anticonvulsant, a neuroprotective agent, a mouse metabolite, a human metabolite and a Daphnia magna metabolite. It is a conjugate acid of a carnosinate. It is a tautomer of a carnosine zwitterion.
Source: PubChem
US FDA substance register · UNII 8HO6PVN24W · registered name CARNOSINE · single chemical substance
Cosmetic roles
Safety & regulatory references
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name カルノシン: 本品は、次の化学式で表されるジペプチドである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 305-84-0
- EC No.EU chemical inventory number
- 206-169-6
- EC No.EU chemical inventory number
- 206-169-9
- DTXSIDUS EPA chemical ID
- DTXSID80879594
- DTXCIDUS EPA compound ID
- DTXCID301017603
- IUPAC
- beta-Alanyl-L-histidine
- Molecular formula
- C9H14N4O3
- Molecular weight
- 226.236 g/mol
Measured properties
- Appearance
- Solid, [Merck Index] White crystalline solid, [Sigma-Aldrich MSDS] · Solid
- Melting point
- 253 - 256 °C
- Solubility
- 384 mg/mL
- Melting/freezing point
- 260 ℃
- n-Octanol/water partition coefficient (Kow)
- -1.810
- Molecular weight
- 226.27
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner3
Source: US EPA CompTox dashboard
Related literature
- Topical Transdermal Administration of Supramolecular Self‐Assembled Carnosine for Anti‐Melanin and Anti‐Aging · 2024
- Lipidome Investigation of Carnosine Effect on Nude Mice Skin to Prevent UV-A Damage · 2023
- Carnosine suppresses human colorectal cancer cell proliferation by inducing necroptosis and autophagy and reducing angiogenesis · 2021
- Evaluation of the Transepidermal Penetration of a Carnosine Complex in Gel Formulation by 3D Skin Models · 2018
- Effect of Carnosine on Physico-Chemical and Antioxidant Activity Properties of FSG-CaCO3 Composite Films · 2016
Linked databases 16
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata 2