Caryophyllene oxide is an epoxide.
Definition
Caryophyllene oxide is an epoxide. It has a role as a metabolite.
Source: PubChem
US FDA substance register · UNII S2XU9K448U · registered name .BETA.-CARYOPHYLLENE OXIDE · single chemical substance
Cosmetic roles
Gives the product a scentPERFUMING
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
CARYOPHYLLENE OXIDEINCI5-Oxatricyclo[8.2.0.04,6]dodecane, 4,12,12-trimethyl-9-methylene-, [1R-(1R*,4R*,6R*,10S*)]-Synonym
- CAS No.chemical registry number
- 1139-30-6
- EC No.EU chemical inventory number
- 214-519-7
- DTXSIDUS EPA chemical ID
- DTXSID4051586
- DTXCIDUS EPA compound ID
- DTXCID8030138
- IUPAC
- (1R,4R,6R,10S)-4,12,12-Trimethyl-9-methylidene-5-oxatricyclo[8.2.0.0~4,6~]dodecane
- Molecular formula
- C15H24O
- Molecular weight
- 220.356 g/mol
Measured properties
- Appearance
- Fine colorless crystals, [MSDSonline] · Colourless solid, Sweet fruity aroma
- Solubility
- Insoluble in water, Soluble in fat · Soluble (in ethanol)
- Melting/freezing point
- 62.95 ℃
- Initial boiling point and range
- 263.48 ℃
- Vapour pressure
- 0.01 ㎜Hg (25°C)
- Water solubility
- 2.21 ㎎/ℓ (25 °C)
- n-Octanol/water partition coefficient (Kow)
- 4.91(EPISUITE)
- Molecular weight
- 220.35
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance5
- Flavouring and nutrient3
Source: US EPA CompTox dashboard
Related literature
- Transethosomal system for enhanced transdermal delivery and therapeutic effect of caryophyllene oxide. · 2024
- Correlation between the Skin Permeation Profile of the Synthetic Sesquiterpene Compounds, Beta-Caryophyllene and Caryophyllene Oxide, and the Antiedematogenic Activity by Topical Application of Nanoemulgels · 2022
- Chemical Composition, Biological Activities and In Silico Analysis of Essential Oils of Three Endemic Prangos Species from Turkey · 2022
- Essential Oil Variability of Superior Myrtle (Myrtus communis L.) Accessions Grown under the Same Conditions · 2022
- Annual Phytochemical Variations and Antioxidant Activity within the Aerial Parts of Lavandula angustifolia, an Evergreen Medicinal Plant · 2022
Linked databases 15
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata