Catalase is an enzyme found in animals, plants, bacteria and fungi.
Definition
US FDA substance register · UNII A7I0CI22DA · registered name CATALASE (BOS TAURUS) · protein
Catalase is an enzyme found in animals, plants, bacteria and fungi.
Cosmetic roles
Safety & regulatory references
- Banned
- ASEAN · European Union · United Kingdom
- Restricted or banned
- Argentina · ASEAN · Brazil · China · European Union · South Korea
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · UK cosmetics regulations (OPSS) · MFDS (Korea) cosmetic regulatory information
Canada
- Warnings and Cautionary Statements: (to the effect of) : "This product is not intended for use on broken or abraded skin."
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex II (prohibited substances), entry 74
Restriction II/74
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name カタラーゼ: 本品は、動物、植物、細菌又はカビ由来の酵素である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 9001-05-2
- EC No.EU chemical inventory number
- 232-577-1
- DTXSIDUS EPA chemical ID
- DTXSID8093782
Measured properties
- Appearance
- liquid
- Relative density
- 1.06 (at 20℃)
- Molecular weight
- 247
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner4
- Chemical reaction regulator3
- Cleaning agent1
- Stabilizing agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 2002 according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) 2012 according to
Source: US EPA CompTox dashboard
Related literature
- A Cross-sectional Study of the Catalase Genetic Polymorphism (-262 cytosine/ thymine) and Blood Catalase Activity among Jordanian Vitiligo Patients · 2023
- Catalase-loaded polymersomes as a promising safe ingredient to active photoprotection · 2021
- Evaluation of Skin Photo-stress Using Catalase · 2010
- Human Serum IgE Reacts with a Metarhizium anisopliae Fungal Catalase · 2009
- Transcriptional repression of catalase in mouse skin tumor progression. · 2004
Linked databases 18
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- Health Canada Cosmetic Ingredient Hotlist
- JCIA labelling names (Japan)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3 4
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS) 2 3
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese