Ceramide AP, formerly known under the INCI name Ceramide 6 II, is the N-acylated sphingolipid consisting of Phytosphingosine having the D-erythro structure linked to an alpha-hydroxy saturated or unsaturated fatty acid.
- Skin barrier C
- Dryness C
- Amount studies used
- formula ratio
- When
- morning and evening
- Irritation
- low
Grades were set by reading this ingredient’s studies. They describe the ingredient, not every product that contains it.
How much products actually contain
54 products state the amountmedian 0.000005%
- under 0.01% 54
- 0.01–0.1% 0
- 0.1–1% 0
- 1% or more 0
Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.
Of the products containing it, 157 list it before the 1% line and 337 after it (usually 1% or less).
Clinical evidence grade by skin concern
- C
- uncontrolled or multi-ingredient studies
Products using this ingredient
12 of 494 confirmed · likeliest to carry enough first · See all 494
NoilyNOILYSKIN ALL-IN-ONE MILKY BUBBLE TONER0.0005% stated
CourcellesMakeup Care Cream0.00005% stated
BRTCCeramide 3-Days Toner0.0000005% stated
Dr.BangGiWonCicamide Blemish Calming All-in-One0.0000001% stated
cocokindcocokind jumbo ceramide barrier serumamount unknown
cocokindcocokind travel-size milky-soft face and body cleanseramount unknown
ROUND LABSoybean Panthenol Ampouleamount unknown
ROUND LABROUND LAB Soybean Panthenol Ampoule 50mlamount unknown
CurlsmithCurlsmith Moisture Memory Releaseamount unknown
TorridenTorriden SOLID IN Essenceamount unknown
Glow RecipeGlow Recipe Avocado Ceramide Recovery Serumamount unknown
BubbleBubble Day Dreamamount unknown
Definition
US FDA substance register · UNII 4370DF050B · registered name CERAMIDE NP · mixture
Ceramide AP, formerly known under the INCI name Ceramide 6 II, is the N-acylated sphingolipid consisting of Phytosphingosine having the D-erythro structure linked to an alpha-hydroxy saturated or unsaturated fatty acid.
Cosmetic roles
Safety & regulatory references
Reviewed by CIR: Safety Assessment of Ceramides as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name セラミドＡＰ: 本品は、α-ヒドロキシ飽和脂肪酸又はα-ヒドロキシ不飽和脂肪酸が結合したD－エリトロ形のフィトスフィンゴシン（＊）からなるＮ－アシル化スフィンゴリピドである。
Source: JCIA labelling names (Japan)
JCIA labelling name セラミドＡＳ: 本品は、α-ヒドロキシ飽和脂肪酸又はα-ヒドロキシ不飽和脂肪酸に結合したD-エリトロ形のスフィンゴシンからなるN-アシル化スフィンゴリピドである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 100403-19-8
- EC No.EU chemical inventory number
- 309-560-3
- EC No.EU chemical inventory number
- 309-560-3 (I)
- DTXSIDUS EPA chemical ID
- DTXSID70146464
What products actually use it for
What the 10 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner8
- Humectant2
Source: US EPA CompTox dashboard
Related literature
- Horse-Derived Ceramide Accentuates Glucosylceramide Synthase and Ceramide Synthase 3 by Activating PPARβ/δ and/or PPARγ to Stimulate Ceramide Synthesis · 2023
- Study of the Repair Action and Mechanisms of a Moisturizing Cream on an SLS-Damaged Skin Model Using Two-Photon Microscopy · 2025
- Exogenous Ceramide Serves as a Precursor to Endogenous Ceramide Synthesis and as a Modulator of Keratinocyte Differentiation · 2022
- Surface-active extracts from plants rich in saponins – effect on lipid mono- and bilayers · 2021
- Comment on “Clinical significance of the water retention and barrier function‐improving capabilities of ceramide‐containing formulations: A qualitative review” · 2021
Linked databases 9
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2 3
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary 2
- MFDS (Korea) cosmetic ingredient register 2
- Tlooto literature search 2 3 4 5
- US Cosmetic Ingredient Review (CIR) 2 3 4
- US EPA CompTox dashboard
- US FDA Unique Ingredient Identifier (UNII)