Cetyltrimethylammonium bromide is the organic bromide salt that is the bromide salt of cetyltrimethylammonium; one of the components of the topical antiseptic cetrimide.
- Korean limit
- 0.1%
How much products actually contain
No product states its amount yet.
Of the products containing it, 3 list it before the 1% line and 15 after it (usually 1% or less).
Products using this ingredient
12 of 18 confirmed · likeliest to carry enough first · See all 18
Not Your Mother'sNot Your Mother's Conditioner
OLAPLEXOLAPLEX Pro Exclusive: 4-In-1 Moisture Mask
LOMALOMA Daily Conditioner 355ml
BIODERMASensibio H2O 850ml (Micellar Water)
BIODERMASensibio H2O 500ml
BIODERMASensibio H2O 100ml (Micellar Water)
BIODERMASensibio H2O 500ml, 2-Pack
BIODERMASensibio H2O, 500ml, 1pc
BIODERMASensibio H₂O Micellar Water 500 ml
BIODERMAHydrabio Tonic Lotion 500ml
BIODERMAHydrabio H2O 500ml
BIODERMASebium H2O 500ml
Definition
Cetyltrimethylammonium bromide is the organic bromide salt that is the bromide salt of cetyltrimethylammonium; one of the components of the topical antiseptic cetrimide. It has a role as a detergent and a surfactant. It is a quaternary ammonium salt and an organic bromide salt. It contains a cetyltrimethylammonium ion.
Source: PubChem
US FDA substance register · UNII L64N7M9BWR · registered name CETRIMONIUM BROMIDE · single chemical substance
Cetrimonium Bromide is a quaternary ammonium salt that conforms generally to the formula:
Cosmetic roles
Safety & regulatory references
- Restricted
- South Korea
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Maximum concentration permitted at final product : 0.1%
ASEAN
- Maximum authorised concentration in the finished cosmetic product : 0.1%
Taiwan
- Maximum concentration : 0.1%
China
- Maximum concentration : (a) 0.25%
- (b)
European Union
- Maximum concentration in ready for use preparation : 0.1%
Source: MFDS (Korea) cosmetic regulatory information
Korea’s toxic-substance GHS classification: Danger · H318 (category 1) · H315 (category 2) · H302 (category 4) · +2 more
Restriction V/44
Source: EU CosIng ingredient list
Reviewed by CIR: Safety Assessment of Trimoniums as used in Cosmetics
Reviewed by CIR: Final Report on the Safety Assessment of Cetrimonium Chloride, Cetrimonium Bromide, and Steartrimonium Chloride
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name セトリモニウムブロミド: 本品は、次の化学式で表される４級アンモニウム塩である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 57-09-0
- EC No.EU chemical inventory number
- 200-311-3
- DTXSIDUS EPA chemical ID
- DTXSID5037028
- DTXCIDUS EPA compound ID
- DTXCID3017028
- IUPAC
- N,N,N-Trimethylhexadecan-1-aminium bromide
- Molecular formula
- C19H42BrN
- Molecular weight
- 364.456 g/mol
Measured properties
- Appearance
- Dry Powder · White powder, [MSDSonline]
- Colour
- white
- pH
- 5~7
- Melting/freezing point
- 237 ℃
- Flash point
- 244 ℃
- Vapour pressure
- 0 ㎩( 25 °C)
- Water solubility
- 55 g/ℓ( 20 °C)
- Vapour density
- 0.5
- n-Octanol/water partition coefficient (Kow)
- 3.18 (calc. EPI Suite TM, Verison 4.0)
- Auto-ignition temperature
- 210 ℃
- Molecular weight
- 364.45
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 14 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Surfactant (surface active agent)3
- Biocide3
- Anti-static agent3
- Preservative2
- Emulsifier2
- Processing aids not otherwise specified1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 7 studies
- Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: Appraisal of the Safety of Chemicals in Foods, Drugs, and Cosmetics according to - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Classification not possible
Skin Sensitization · Screening - Category 2
Skin Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Category 2A
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Inhibitor mixture for reducing bacteria growth and corrosion on marine steel† · 2022
- Nano-Biochar Derived from Bamboo Biomass: A Dual-Functional Material for Electrochemical Sensing of Ferulic Acid and Adsorptive Removal of Surfactants in Cosmetic Wastewater · 2025
- Quaternary Ammonium Compounds and Contact Dermatitis: A Review and Considerations During the COVID-19 Pandemic · 2023
- Allergic contact dermatitis caused by an antiseptic containing cetrimide · 2015
- Occupational allergic contact dermatitis from alkylammonium amidobenzoate. · 2001
Linked databases 22
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese