Hexadecan-1-ol is a long-chain primary fatty alcohol that is hexadecane substituted by a hydroxy group at position 1.
How much products actually contain
No product states its amount yet.
Of the products containing it, 1,030 list it before the 1% line and 274 after it (usually 1% or less).
Products using this ingredient
12 of 1,285 confirmed · likeliest to carry enough first · See all 1,285
TeenwellHair Balance Ritual Treatment Bar
VerbVerb Curl Cream
SidmoolScalp Hills Panthenol Rinse Bar
DonggubatDonggubat Treatment Bar
DonggubatDonggubat Rinse Bar
DonggubatDonggubat Vegan Treatment Bar Camellia
107Hair & Scalp Hydrating Microbiome Treatment 180ml
OLAPLEXOLAPLEX Pro Exclusive: Weightless Nourishing Mask
OLAPLEXOLAPLEX Weightless Nourishing Mask
Elizabeth ArdenElizabeth Arden Red Door Cream Deodorant
OUAIOUAI Thick Hair Treatment Masque - Travel
Living ProofLiving Proof Full Conditioner + Refill
Definition
Hexadecan-1-ol is a long-chain primary fatty alcohol that is hexadecane substituted by a hydroxy group at position 1. It has a role as a flavouring agent, a plant metabolite, a human metabolite and an algal metabolite. It is a hexadecanol and a long-chain primary fatty alcohol.
Source: PubChem
US FDA substance register · UNII 936JST6JCN · registered name CETYL ALCOHOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report on the Safety Assessment of Cetearyl Alcohol, Cetyl Alcohol, Isostearyl Alcohol, Myristyl Alcohol, and Behenyl Alcohol
Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2005/2006
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name セタノール: 本品は、次の化学式で表される脂肪族アルコールである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 36653-82-4
- EC No.EU chemical inventory number
- 253-149-0
- DTXSIDUS EPA chemical ID
- DTXSID4027991
- DTXCIDUS EPA compound ID
- DTXCID607991
- IUPAC
- Hexadecan-1-ol
- Molecular formula
- C16H34O
- Molecular weight
- 242.447 g/mol
Measured properties
- Appearance
- Liquid, Wet Solid, Other Solid, Dry Powder · White solid, [Hawley]
- Odour
- Faint odor · ODORLESS
- Boiling point
- 344 · 334 °C at 760 mm Hg
- Melting point
- 49.3 · 49.3 °C
- Solubility
- Insoluble · Slightly soluble in alcohol, soluble in acetone, very soluble in ether, benzene, chloroform
- Density
- 0.8187 at 50 °C/4 °C · 0.8152 (55 °C)
- Viscosity
- 53 mPa-s (=cP) at 75 °C · 4.55 cP (80℃)
- Dissociation constant
- pKa = 16.20
- Colour
- white
- Melting/freezing point
- 49 ℃
- Initial boiling point and range
- 344 ℃(1013 hPa 20℃)
- Flash point
- 175 ℃(ca.)
- Upper/lower flammability or explosive limits
- 8 / 1 %
- Vapour pressure
- ( 0.0022hPa 20℃)
- Water solubility
- 0.012 ㎎/ℓ (25℃)
- Vapour density
- 8.360
- Relative density
- 0.8176 (50℃)
- n-Octanol/water partition coefficient (Kow)
- 6.65
- Auto-ignition temperature
- 251 ℃
- Molecular weight
- 242.45
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 176 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Viscosity modifier64
- Emulsifier33
- Thickening agent21
- Plasticizer12
- Softener and conditioner8
- Opacifer6
- Solvent4
- Lubricating agent4
13 other uses
- Surfactant (surface active agent)4
- Fragrance3
- Flavouring and nutrient3
- Stabilizing agent2
- Processing aids not otherwise specified2
- Foamant2
- Deodorizer2
- Antioxidant1
- Intermediate1
- Vapor pressure modifiers1
- Solubility enhancer1
- No specific technical function1
- Monomers1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Category 6.3B (Category 3)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- OPTIMIZATION OF VCO LOTION PREPARATIONS WITH VARIATIONS CETYL ALCOHOL AND CARRAGEEN CONCENTRATIONS USING SLD METHOD · 2024
- Effect Of Cetyl Alcohol Variation On Formulation And Stability Of Belimbing Wuluh Leaf Extract (Averrhoa Bilimbi L.) Cream · 2026
- Formulation of Fermented Earthworm (Lumbricus rubellus) Lotion as a Therapy for Atopic Dermatitis · 2025
- Cetyl alcohol, stearyl alcohol and colloidal oatmeal-based gentle skin cleanser in management of dry and sensitive skin: a cross-sectional study · 2023
- Allergic Contact Dermatitis to Cetyl Alcohol · 2011
Linked databases 21
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese