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Ingredient Dictionary

CETYL PALMITATE

Palmityl palmitate is a palmitate ester resulting from the formal condensation of palmitic acid with palmityl alcohol.

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 138 list it before the 1% line and 46 after it (usually 1% or less).

Products using this ingredient

12 of 180 confirmed · likeliest to carry enough first · See all 180

Definition

Palmityl palmitate is a palmitate ester resulting from the formal condensation of palmitic acid with palmityl alcohol. It is used as a thickener and emollient in cosmetics. It has a role as a metabolite. It is functionally related to a hexadecan-1-ol.

Source: PubChem

US FDA substance register · UNII 5ZA2S6B08X · registered name Cetyl palmitate · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Makes skin soft and smoothSKIN CONDITIONING - EMOLLIENTKeeps skin in good condition (CosIng catch-all)SKIN CONDITIONINGListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2002/2003

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Octyl Palmitate, Cetyl Palmitate and Isopropyl Palmitate

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Safety Assessment of Alkyl Esters as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name パルミチン酸セチル: 本品は、パルミチン酸（＊）とセタノール（＊）のエステルであり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

CETYL PALMITATEINCI세틸팔미테이트Korean label name (MFDS standard)Hexadecanoic acid, hexadecyl esterSynonymパルミチン酸セチルJapanese labelling name
CAS No.chemical registry number
540-10-3
EC No.EU chemical inventory number
208-736-6
DTXSIDUS EPA chemical ID
DTXSID5047114
DTXCIDUS EPA compound ID
DTXCID3027114
IUPAC
Hexadecyl hexadecanoate
Molecular formula
C32H64O2
Molecular weight
480.862 g/mol

Measured properties

Appearance
Liquid, Large Crystals · solid
Colour
white
Melting/freezing point
54 ℃
Initial boiling point and range
534 ℃(760mmHg)
Flash point
269 ℃
Vapour pressure
0.0000000002 ㎜Hg(25℃)
Vapour density
16.6
Relative density
0.989 (20℃)
n-Octanol/water partition coefficient (Kow)
14.61 (est.)
Molecular weight
480.96

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 30 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Softener and conditioner13
  • Fragrance3
  • Lubricating agent3
  • Emulsifier3
  • Viscosity modifier2
  • Deodorizer2
  • Humectant1
  • Anti-adhesive/cohesive1
2 other uses
  • Soil amendments1
  • Density modifier1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 1 eye studies are on record.

Classed as low4

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 5 studies
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation)
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 1981 according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) adopted in 2015 equivalent or similar to
  • Not likely to be sensitizing
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) 2002 according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) according to EPA OPPTS 870.2600 (Skin Sensitisation) 2003
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to

Source: US EPA CompTox dashboard

Related literature

Linked databases 21

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