CHLORHEXIDINE DIHYDROCHLORIDE

US FDA substance register · UNII E64XL9U38K · registered name Chlorhexidine Hydrochloride · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Chlorhexidine hydrochloride is a member of guanidines.

Source: PubChem

Chlorhexidine Dihydrochloride is a salt of Chlorhexidine and hydrochloric acid. It conforms generally to the formula:

Restricted

China · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Argentina · Brazil

• Maximum concentration permitted at final product : 0.3% (expressed as chlorhexidine)

ASEAN

• Maximum authorised concentration in the finished cosmetic product : 0.3% expressed as chlorhexidine

Taiwan

• 0.3%

Japan

• Maximum amount per 100 g (Cosmetics not used for mucosa and to be washed away) : 0.10 g
• Maximum amount per 100 g (Cosmetics not used for mucosa and not to be washed away) : 0.10 g
• Maximum amount per 100 g (Cosmetics that may be used for mucosa) : 0.0010 g

European Union

• Maximum concentration in ready for use preparation : 0.3% (as chlorhexidine)

Health Canada Cosmetic Ingredient Hotlist · restricted with conditions

Source: Health Canada Cosmetic Ingredient Hotlist

Restriction V/42 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Chlorhexidine/Chlorhexidine Diacetate/Chlorhexidine Dihydrochloride/Chlorhexidine Digluconate

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Note Regarding the Safety Assessment of Chlorhexidine, Chlorhexidine Diacetate, Chlorhexidine Digluconate, and Chlorhexidine Dihydrochloride

Source: US Cosmetic Ingredient Review (CIR)