CHLORHEXIDINE

美国FDA 物质登记 · UNII R4KO0DY52L · 登记名称 CHLORHEXIDINE · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

Chlorhexidine is an organic compound that conforms to the formula:

Chlorhexidine is a bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge. It has a role as an antibacterial agent and an antiinfective agent. It is a member of biguanides and a member of monochlorobenzenes. It is functionally related to a biguanide.

来源: PubChem

限用

韩国 · 中国

准用防腐剂

英国

来源: 加拿大禁用·限用成分清单 · 韩国食药处 化妆品法规信息 · 欧盟化妆品法规 · 日本化妆品标准 · 台湾FDA 化妆品成分 · 英国化妆品法规

阿根廷 · 巴西

• Maximum concentration permitted at final product : 0.3% (expressed as chlorhexidine)

东盟

• Maximum authorised concentration in the finished cosmetic product : 0.3% expressed as chlorhexidine

加拿大

• Maximum Concentration Permitted : a) 0.14% calculated as chlorhexidine free base b) 0.19% calculated as chlorhexidine diacetate c) 0.20% calculated as chlorhexidine digluconate d) 0.16% calculated as chlorhexidine dihydrochloride

台湾

• 倘前述三國家地區政府管理有差異時，則採其中限量規定方式最安全者。
• ※ 本表所稱之口腔製劑，包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
• 用途 : 防腐
• 最大配合量 : 0.3 % (以 chlorhexidine 計)
• 0.3%

日本

• 每100g最大配合量 (Cosmetics not used for mucosa and to be washed away) : 0.10 g
• 每100g最大配合量 (Cosmetics not used for mucosa and not to be washed away) : 0.050 g
• 每100g最大配合量 (Cosmetics that may be used for mucosa) : 0.050 g

欧盟

• Maximum concentration in ready for use preparation : 0.3% (as chlorhexidine)

未列入韩国有毒物质 GHS 分类

来源: 韩国有毒物质 GHS 信息（环境公团）

Restriction V/42

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010

来源: 美国CIR 安全性评估

Reviewed by CIR: Final Report on the Safety Assessment of Chlorhexidine/Chlorhexidine Diacetate/Chlorhexidine Dihydrochloride/Chlorhexidine Digluconate

来源: 美国CIR 安全性评估

Reviewed by CIR: Note Regarding the Safety Assessment of Chlorhexidine, Chlorhexidine Diacetate, Chlorhexidine Digluconate, and Chlorhexidine Dihydrochloride

来源: 美国CIR 安全性评估