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Ingredients

Ingredient Dictionary

CHLOROBUTANOL

Chlorobutanol is a tertiary alcohol.

Korean limit
0.50%
Molecular structure

Definition

Chlorobutanol is a tertiary alcohol.

Source: PubChem

US FDA substance register · UNII HM4YQM8WRC · registered name Chlorobutanol · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Chlorobutanol is a halogenated alcohol that conforms to the formula:

Cosmetic roles

Stops microbes growing in the productPRESERVATIVE

Safety & regulatory references

Allowed preservative
United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Japan Standards for Cosmetics · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)

Argentina · Brazil

  • Maximum concentration permitted at final product : 0.5%
  • Other limitations and requirements : Banned in sprayable systems (such as aerosols and sprays)
  • Use conditions and warnings that must appear on the label : It contains chlorobutanol

ASEAN

  • Maximum authorised concentration in the finished cosmetic product : 0.5%
  • Other limitations and requirements : Prohibited in aerosol dispensers (sprays)
  • Conditions of use and warning which must be printed on the labels : - Contains chlorobutanol

Taiwan

  • Maximum concentration : 0.5%
  • 0.5%

Japan

  • Maximum amount per 100 g(Maximum amount of ingredient per 100 g) : 0.10(0.10 g)

China

  • Maximum concentration : 0.5%

South Korea

  • Maximum concentration : 0.50%

European Union

  • Maximum concentration in ready for use preparation : 0.5%
  • Other : Not to be used in aerosol dispensers (sprays)
  • Wording of conditions of use and warnings : Contains Chlorobutanol

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex V (allowed preservatives), entry 11 · maximum concentration 0.5%

Source: EU allowed preservatives (Annex V)

Restriction V/11

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name クロロブタノール: 本品は、次の化学式で表されるハロゲン化アルコールである。

Source: JCIA labelling names (Japan)

Names & identifiers

CHLOROBUTANOLINCI클로로부탄올Korean label name (MFDS standard)2-Propanol, 1,1,1-trichloro-2-methyl-SynonymクロロブタノールJapanese labelling name
CAS No.chemical registry number
57-15-8
EC No.EU chemical inventory number
200-317-6
DTXSIDUS EPA chemical ID
DTXSID1041217
DTXCIDUS EPA compound ID
DTXCID9021217
IUPAC
1,1,1-Trichloro-2-methylpropan-2-ol
Molecular formula
C4H7Cl3O
Molecular weight
177.45 g/mol

Measured properties

Appearance
Colorless to white solid, [Merck Index] Crystalline solid, [MSDSonline] · NEEDLES (WATER+1)
Odour
Camphor odor · Characteristic odor
Boiling point
167 · 167 °C
Melting point
99 · 97 °C
Solubility
INSOL IN COLD WATER, SOL IN HOT WATER · 1 G IN 125 ML WATER, SOL IN VOLATILE OILS
Stability
EMPLOYED IN SOLN @ PH 5 OR LOWER, WHICH IS STABLE FOR AT LEAST MANY MO
Colour
white
Melting/freezing point
97 ℃
Initial boiling point and range
167 ℃
Flammability (solid, gas)
combustible
Vapour pressure
0.833 ㎜Hg (@ 25 ℃, est.)
Water solubility
8000 ㎎/ℓ (@ 20 ℃)
Vapour density
6.13
n-Octanol/water partition coefficient (Kow)
2.03
Molecular weight
177.46

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Preservative2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies
  • Category 6.3B (Category 3)
    Skin Irritation · Read Across
  • SkinIrr2
    Skin Irritation · QSAR Predicted
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across

Source: US EPA CompTox dashboard

Related literature

Linked databases 27