5-chlorosalicylic acid is a monohydroxybenzoic acid that is 2-hydroxybenzoic acid (salicylic acid) in which the hydrogen at position 5 is replaced by chlorine.
Definition
5-chlorosalicylic acid is a monohydroxybenzoic acid that is 2-hydroxybenzoic acid (salicylic acid) in which the hydrogen at position 5 is replaced by chlorine. It is a chlorobenzoic acid, a monohydroxybenzoic acid and a member of monochlorobenzenes. It is functionally related to a benzoic acid. It is a conjugate acid of a 5-chlorosalicylate.
Source: PubChem
US FDA substance register · UNII J2YFG68VCZ · registered name 5-CHLOROSALICYLIC ACID · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 321-14-2
- EC No.EU chemical inventory number
- 206-283-9
- DTXSIDUS EPA chemical ID
- DTXSID7059806
- DTXCIDUS EPA compound ID
- DTXCID1038452
- IUPAC
- 5-Chloro-2-hydroxybenzoic acid
- Molecular formula
- C7H5ClO3
- Molecular weight
- 172.56 g/mol
Measured properties
- Appearance
- (nd(w,al))
- Melting/freezing point
- 171.5 ℃(EXP)
- Initial boiling point and range
- 320.71 ℃(EST)
- Vapour pressure
- 0.0000258 ㎜Hg (EST at 25 deg C)
- Water solubility
- 10000 ㎎/ℓ (EXP at 25 deg C)
- n-Octanol/water partition coefficient (Kow)
- 3.09 (EXP)
- Molecular weight
- 172.57
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinSens1
Skin Sensitization · QSAR Predicted
Source: US EPA CompTox dashboard
Linked databases 13
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata