CHLORPHENESIN

US FDA substance register · UNII I670DAL4SZ · registered name CHLORPHENESIN · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Chlorphenesin is the organic compound that conforms to the formula:

Chlorphenesin is glycerol in which the hydrogen of one of the primary hydroxy groups is substituted by a 4-chlorophenyl group. It has antifungal and antibacterial properties, and is used for treatment of cutaneous and vaginal infections. Its 1-carbamate is used as a skeletal muscle relaxant for the treatment of painful muscle spasm. It has a role as an antibacterial drug, a muscle relaxant and an antifungal drug. It is a glycol, a member of propane-1,2-diols and a member of monochlorobenzenes.

Source: PubChem

Allowed preservative

United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Japan Standards for Cosmetics · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)

Argentina · Brazil

• Maximum concentration permitted at final product : 0.3%

ASEAN

• Maximum authorised concentration in the finished cosmetic product : 0.3%

Taiwan · China

• Maximum concentration : 0.3%

Japan

• Maximum amount per 100 g (Cosmetics not used for mucosa and to be washed away) : 0.30 g
• Maximum amount per 100 g (Cosmetics not used for mucosa and not to be washed away) : 0.30 g

South Korea

• Maximum concentration : 0.30%

European Union

• Maximum concentration in ready for use preparation : 0.3%

EU Cosmetics Regulation, Annex V (allowed preservatives), entry 50 · maximum concentration 0.3%

Source: EU allowed preservatives (Annex V)

Restriction V/50

Source: EU CosIng ingredient list

Reviewed by CIR: Safety Assessment of Chlorphenesin as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)