Cholesteryl oleate is the (Z)-stereoisomer of cholesteryl octadec-9-enoate.
How much products actually contain
No product states its amount yet.
Of the products containing it, 2 list it before the 1% line and 0 after it (usually 1% or less).
Products using this ingredient
2 of 2 confirmed · likeliest to carry enough first
Definition
Cholesteryl oleate is the (Z)-stereoisomer of cholesteryl octadec-9-enoate. It has a role as a mouse metabolite. It is a CE(18:1) and a cholesteryl octadec-9-enoate. It is functionally related to an oleic acid.
Source: PubChem
US FDA substance register · UNII 3DPK9KFN2M · registered name CHOLESTERYL OLEATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name オレイン酸コレステリル: 本品は、オレイン酸（＊）とコレステロール（＊）のエステルである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 303-43-5
- EC No.EU chemical inventory number
- 206-142-1
- DTXSIDUS EPA chemical ID
- DTXSID901014621
- DTXCIDUS EPA compound ID
- DTXCID601437167
- IUPAC
- Cholest-5-en-3beta-yl (9Z)-octadec-9-enoate
- Molecular formula
- C45H78O2
- Molecular weight
- 651.117 g/mol
Measured properties
- Colour
- white
- Melting/freezing point
- 42~49 ℃
- Flash point
- &, gt, 112 ℃
- Upper/lower flammability or explosive limits
- - / - %
- Vapour pressure
- (4E-18 mmHg (25 C))
- n-Octanol/water partition coefficient (Kow)
- 18.79
- Molecular weight
- 651.12
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
- Fragrance1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinIrr2
Skin Irritation · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
- 3D Molecular Imaging of Stratum Corneum by Mass Spectrometry Suggests Distinct Distribution of Cholesteryl Esters Compared to Other Skin Lipids · 2022
- Cholesteryl oleate-appended phthalocyanines as potential photosensitizers in the treatment of leishmaniasis · 2015
- Abstract 329: CRISPR/Cas-mediated Gene Editing in Human iPSC-derived Macrophage Reveals Lysosomal Acid Lipase Functions in Human Macrophages · 2015
- Why does a hydrophilic drug permeate skin, although it is not soluble in white petrolatum? · 2009
- Metabolism and distribution of intramolecular excimer-forming dipyrenebutanoyl glycerophospholipids in human fibroblasts. Marked resistance to metabolic degradation. · 1995
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata