Cholesteryl hemisuccinate is a dicarboxylic acid monoester resulting from the formal condensation of the hydroxy group of cholesterol with one of the carboxy groups of succinic acid.
Definition
Cholesteryl Succinate is the monoester of Cholesterol and Succinic acid
Cholesteryl hemisuccinate is a dicarboxylic acid monoester resulting from the formal condensation of the hydroxy group of cholesterol with one of the carboxy groups of succinic acid. A detergent that is often used to replace cholesterol in protein crystallography, biochemical studies of proteins, and pharmacology. It has a role as a detergent. It is a cholestane ester, a hemisuccinate and a dicarboxylic acid monoester. It is functionally related to a cholesterol.
Source: PubChem
US FDA substance register · UNII T3J4KS4201 · registered name CHOLESTERYL SUCCINATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name コハク酸コレステリル: 本品は、コハク酸（＊）とコレステロール（＊）とモノエステルである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 1510-21-0
- DTXSIDUS EPA chemical ID
- DTXSID10934145
- DTXCIDUS EPA compound ID
- DTXCID801362798
- IUPAC
- 4-[(Cholest-5-en-3beta-yl)oxy]-4-oxobutanoic acid
- Molecular formula
- C31H50O4
- Molecular weight
- 486.737 g/mol
Measured properties
- Water solubility
- 0.00001702 ㎎/ℓ
- n-Octanol/water partition coefficient (Kow)
- 9.49
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinIrr2
Skin Irritation · QSAR Predicted
Source: US EPA CompTox dashboard
Linked databases 14
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata