Chymotrypsin is a class of proteolytic enzymes derived from bovine pancreas.
Definition
US FDA substance register · UNII BVS505O332 · registered name Chymotrypsin · protein
Chymotrypsin is a class of proteolytic enzymes derived from bovine pancreas.
Cosmetic roles
Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONING
More data — names, identifiers, properties, test records, literature
Names & identifiers
CHYMOTRYPSININCI
- CAS No.chemical registry number
- 9004-07-3
- EC No.EU chemical inventory number
- 232-671-2
- EC No.EU chemical inventory number
- 232-671-2 (I)
- DTXSIDUS EPA chemical ID
- DTXSID901010867
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 3 eye studies are on record.
Classed as moderate1
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 7 studies
- Classification not possible
Skin Irritation · Screening - Category 1
Skin Sensitization · Screening - Category 6.3A (Category 2)
Skin Irritation · Read Across - Skin Irrit. 2
Skin Irritation · Authoritative - Category 2A
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Eye Irrit. 2
Eye Irritation · Authoritative
Source: US EPA CompTox dashboard
Related literature
- Proteases and tissue repair: peri operative role of chymotrypsin: trypsin in surgical patients · 2018
- A Bowman-Birk type chymotrypsin inhibitor peptide from the amphibian, Hylarana erythraea · 2018
- A Bowman-Birk type chymotrypsin inhibitor peptide from the amphibian, Hylarana erythraea · 2018
- Quercetin as a Protease (á-Chymotrypsin) Inhibitor · 2014
- Extraction, Purification and Characterization of Fish Chymotrypsin: A Review · 2011